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  • Detlef Balschun, David P Wolfer, +5 authors Hans-Peter Lipp
  • Biology, Medicine
  • The Journal of Neuroscience
  • 2003 (First Publication: 16 July 2003)
  • Previous studies addressing the role of the transcription factor cAMP response element-binding protein (CREB) in mammalian long-term synaptic plasticity and memory by gene targeting were compromisedContinue Reading
  • Kathryn M. Kinross, Karen Montgomery, +18 authors Wayne A Phillips
  • Biology, Medicine
  • The Journal of clinical investigation
  • 2012 (First Publication: 1 February 2012)
  • Mutations in the gene encoding the p110α subunit of PI3K (PIK3CA) that result in enhanced PI3K activity are frequently observed in human cancers. To better understand the role of mutant PIK3CA in theContinue Reading
  • Daniel V. Brown, Gulay Filiz, +7 authors Theo Mantamadiotis
  • Medicine, Biology
  • PloS one
  • 2017 (First Publication: 27 February 2017)
  • Glioblastoma (GBM) is a heterogeneous tumor of the brain with a poor prognosis due to recurrence and drug resistance following therapy. Genome-wide profiling has revealed the existence of distinctContinue Reading