Thengungal Kochupapy Ravi

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BACKGROUND Diabetes mellitus has become an international healthcare crisis that requires new approaches to prevent and treat it. The objective of this study was to evaluate the impact of pharmaceutical care on quality of life (QOL) in patients with type 2 diabetes mellitus. METHODS A prospective study on impact of pharmaceutical care on QOL in patients(More)
The colon specific drug delivery systems based on polysaccharides; locust bean gum and chitosan in the ratio of 2 : 3, 3 : 2 and 4 : 1 were evaluated using in vitro and in vivo methods. The in vitro studies in pH 6.8 phosphate buffer containing 2% w/v rat caecal contents showed that the cumulative percentage release of mesalazine after 26 h were(More)
Residues of Dimethoate present in locally available Spinach varities Palak : Beta maritima, Vendhai : Trigonella foenumgraecum, Thandan : Amarnathus mangostanus green and red were determined. The quantification was carried out using RP-HPLC for unprocessed (fresh) and processed (washed, washed and cooked) Spinach samples. The extraction was carried out with(More)
BACKGROUND Adverse Drug Reactions (ADRs) constitute an enormous burden for the society. The aim of the present study was to detect, document, assess and report the suspected ADRs and preparation of guidelines to minimize the incidence of ADRs. METHODS A prospective-observational study was conducted in the Department of General Medicine of a tertiary care(More)
A series of novel 1-(4-methylcoumarinyl-7-oxyacetyl)-3,5-dimethyl-4(arylazo)pyrazoles and 1-(4-methylcoumarinyl-7-oxyacetyl)-3-methyl-4-(substituted phenyl) hydrazono-2-pyrazolin-5-ones were synthesised and evaluated for antibacterial and antioxidant activities. Compounds 3b, 3g, 5b, 5d and 5g showed good antibacterial activity and compound 5e was found to(More)
.co m) . was displayed by Terminalia chebula seed extract against B. cereus. In fact, this plant extract (both aqueous and ethanolic) could inhibit all the bacterial strains investigated. Out of 50 aqueous extracts, 16 extracts showed activity against any one of grampositive bacteria, while only 10 extracts showed activity against any one of gram-negative(More)
Moxifloxacin and lomefloxacin are fluoroquinolone antibiotics used in treating urinary and respiratory tract infections. Fluoroquinolones are known to have interactions with drugs that are active in gastro intestinal tract. Being moxifloxacin and lomefloxacin fluoroquinolones the interaction study of was carried out with sucralfate, gelusil, erythromycin(More)
Structure-based lead optimization approaches are a major role in the drug-discovery process. In the present work, lead compounds that satisfied Lipinski rule of five, drug likeness score and docking studies performed by using Argus lab 4.0. The designed compounds were evaluated for Xanthine oxidase(XO) inhibition binding ability to identify the new lead(More)
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