Thay-Hsiung Chen

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Autophagy is a crucial process for cells to maintain homeostasis and survival through degradation of cellular proteins and organelles, including mitochondria and endoplasmic reticula (ER). We previously demonstrated that temozolomide (TMZ), an alkylating agent for brain tumor chemotherapy, induced reactive oxygen species (ROS)/extracellular signal-regulated(More)
Cerebral ischemia is a leading cause of mortality and morbidity worldwide, which results in cognitive and motor dysfunction, neurodegenerative diseases, and death. Evodiamine (Evo) is extracted from Evodia rutaecarpa Bentham, a plant widely used in Chinese herbal medicine, which possesses variable biological abilities, such as anticancer, anti-inflammation,(More)
1 ST-segment elevation myocardial infarction (STEMI) is one of the most common cardiovascular diseases in Taiwan. The management strategies for STEMI are to do early diagnosis, minimize delay of medical contact, and administration of reperfusion therapy as rapidly as possible. Initial evaluation in emergency department for STEMI includes concise history(More)
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