Thao Tran

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MOTIVATION The computational identification of non-coding RNA (ncRNA) genes represents one of the most important and challenging problems in computational biology. Existing methods for ncRNA gene prediction rely mostly on homology information, thus limiting their applications to ncRNA genes with known homologues. RESULTS We present a novel de novo(More)
Identification of operons in the hyperthermophilic archaeon Pyrococcus furiosus represents an important step to understanding the regulatory mechanisms that enable the organism to adapt and thrive in extreme environments. We have predicted operons in P.furiosus by combining the results from three existing algorithms using a neural network (NN). These(More)
Finding repetitive sequences in DNA is of particular interest in biology due to their role in genetic diseases, human gene mapping , evolution, and many other important and interesting applications. We propose a method for finding hidden periodicities in DNA based on Fourier analysis. It is shown that this approach is effective for finding new repeat(More)
  • Shanna Smith Jaggars, Di Xu, Melissa Barragan, Rachel Hare Bork, Thao Tran, Zawadi Rucks-Ahidiana
  • 2012
Given the rapid growth in online coursework within higher education, it is important to establish and validate quality standards for these courses. While many online learning quality rubrics do exist, thus far there has been little empirical evidence establishing a clear link between specific aspects of course quality and concrete, student-level course(More)
Late gadolinium enhanced (LGE) cardiovascular magnetic resonance (CMR) has proven to be the gold standard for viability assessment. LGE CMR is also useful for identifying the nature of cardiac masses or lesions. We report a case of a rare primary cystic tumor of the atrioventricular node, in which CMR proved to be valuable.
A pseudoaneurysm occurs when incomplete rupture of the heart seals within organizing thrombus, hematoma, and pericardium and maintains communication with the left ventricle. A pseudoaneurysm may cause arterial emboli and drain off a considerable portion of ventricular stroke volume. Cardiovascular magnetic resonance imaging proves to be an adequate(More)
The evolution of polymer based nanoparticles as a drug delivery carrier via pharmaceutical nano/microencapsulation has greatly promoted the development of nano-and micro-medicine in the past few decades. Poly(lactide-co-glycolide) (PLGA) and chitosan, which are biodegradable and biocompatible polymers, have been approved by both the Food & Drug(More)
Retroviruses selectively package two copies of their unspliced genomes by what appears to be a dimerization-dependent RNA packaging mechanism. Dimerization of human immunodeficiency virus Type-1 (HIV-1) genomes is initiated by “kissing” interactions between GC-rich palindromic loop residues of a conserved hairpin (DIS), and is indirectly promoted by(More)
Current patient selection criteria for Cardiac Resynchronization Therapy (CRT), an efficacious treatment for heart failure, include no measure of disconjugate cardiac contractility other than prolonged QRS on electrocardiogram. Using cardiac magnetic resonance imaging, we examined the roles of cardiac asymmetry, asynchrony, and circumferential strain in DCC(More)