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The authors developed an electrocardiography-triggered M-mode navigator-echo technique to help monitor cardiac motion and identify the period of minimal cardiac motion in the cardiac cycle. Coronary magnetic resonance angiography was performed in eight healthy adult volunteers and one patient with heart disease. To minimize cardiac motion effects, trigger(More)
Time-resolved imaging is crucial for the accurate diagnosis of liver lesions. Current contrast enhanced liver magnetic resonance imaging acquires a few phases in sequential breath-holds. The image quality is susceptible to bolus timing errors, which could result in missing the critical arterial phase. This impairs the detection of malignant tumors that are(More)
Quantitative assessment of myelination is important for characterizing tissue damage and evaluating response to therapy in white matter diseases such as multiple sclerosis. Conventional multicomponent T(2) relaxometry based on the two-dimensional (2D) multiecho spin echo sequence is a promising method to measure myelin water fraction, but its clinical(More)
Fast methods using balanced steady-state free precession have been developed to reduce the scan time of T₁ and T₂ mapping. However, flip angle (FA) profiles created by the short radiofrequency pulses used in steady-state free precession deviate substantially from the ideal rectangular profile, causing T₁ and T₂ mapping errors. The purpose of this study was(More)
PURPOSE To develop a rapid navigator-gated three-dimensional (3DNAV) delayed-enhancement MRI (DE-MRI) sequence for myocardial viability assessment, and to evaluate its performance with breathhold two-dimensional (2DBH) DE-MRI sequence as the reference standard. MATERIALS AND METHODS 2DBH DE-MRI was initiated 10 minutes after contrast administration and(More)
For pharmacokinetic modeling of tissue physiology, there is great interest in measuring the arterial input function (AIF) from dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) using paramagnetic contrast agents. Due to relaxation effects, the measured signal is a nonlinear function of the injected contrast agent concentration and depends on(More)
A respiratory and cardiac self-gated free-breathing three-dimensional cine steady-state free precession imaging method using multiecho hybrid radial sampling is presented. Cartesian mapping of the k-space center along the slice encoding direction provides intensity-weighted position information, from which both respiratory and cardiac motions are derived.(More)
Motion artifacts in MRI may be reduced by optimized view ordering. Extensive simulations of view-ordering techniques were performed on high-resolution phantom images to determine the best strategy for distributing motion in k-space. Although not exhaustive, simulation results indicate that minimizing motion at the center of k-space is critical to overall(More)
PURPOSE To examine the feasibility of flow-independent T2-prepared inversion recovery (T2IR) black-blood (BB) magnetization preparation for three-dimensional (3D) balanced steady-state free precession (SSFP) vessel wall MRI of the popliteal artery, and to evaluate its performance relative to flow-dependent double inversion recovery (DIR), spatial(More)