Tetsuya Tsujikawa

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UNLABELLED Benign and malignant pulmonary lesions usually are differentiated by 18F-FDG PET with a semiquantitative 18F-FDG standardized uptake value (SUV) of 2.5. However, the frequency of malignancies with an SUV of <2.5 is significant, and pulmonary nodules with low 18F-FDG uptake often present diagnostic challenges. METHODS Among 360 consecutive(More)
Understanding tumor-specific metabolism under hypoxia is important to find novel targets for antitumor drug design. Here we found that tumor cells expressed higher levels of cytosolic acetyl-CoA synthetase (ACSS2) under hypoxia than normoxia. Knockdown of ACSS2 by RNA interference (RNAi) in tumor cells enhanced tumor cell death under long-term hypoxia in(More)
UNLABELLED The grade of histologic differentiation is one of the most important prognostic factors in patients with endometrial carcinoma and postoperative staging. The aim of this study was to investigate whether 16alpha-(18)F-fluoro-17beta-estradiol ((18)F-FES) and (18)F-FDG PET reflect clinicopathologic features in patients with endometrial tumors. (More)
UNLABELLED The objective of this study is to reevaluate the clinical significance of 1-11C-acetate (ACE) positron emission tomography (PET) in patients with brain glioma, in comparison with 18F-fluorodeoxyglucose (FDG) PET. METHODS Ten patients with histologically proven glioma were included in this study. They underwent PET examination with both FDG and(More)
The aim of this study is to evaluate the reproducibility of semi-quantitative parameters obtained from two 2-deoxy-2-[F-18]fluoro-d-glucose-positron emission tomography (FDG–PET) studies using two different PET scanners. Forty-five patients underwent FDG–PET examination with two different PET scanners on separate days. Two PET images with different(More)
PURPOSE Kikuchi-Fujimoto disease (KFD), formerly called subacute necrotizing lymphadenitis, is a rare cause of cervical lymphadenopathy. The purpose of this study was to evaluate the usefulness of FDG PET/CT for distinguishing KFD from non-Hodgkin lymphoma (NHL). MATERIALS AND METHODS Twenty-two patients with cervical lymphadenopathy (8 with KFD and 14(More)
PURPOSE To clarify the roles of serial MR spectroscopy (MRS) and continuous arterial spin labeling (CASL) perfusion images for evaluating cerebral lesions in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). MATERIALS AND METHODS Two cases of MELAS followed up serially using MRS and CASL images in(More)
The benefits of multi-detector row CT (MDCT) relative to single-detector row helical CT are considerable. Multi-detector row CT allows shorter acquisition times, greater coverage, and superior image resolution. These factors substantially increase the diagnostic accuracy of the examination. Three-dimensional (3D) volume data from MDCT provides various(More)
The most frequently used molecular imaging technique is currently 18F-deoxy-glucose (FDG) positron emission tomography (PET). FDG-PET holds promise in the evaluation of recurrent or residual ovarian cancer when CA125 levels are rising and conventional imaging, such as ultrasound, CT, or MRI, is inconclusive or negative. Recently, integrated PET/CT, in which(More)
PURPOSE To clarify prospectively the relationship between estrogen receptor (ER) expression and glucose metabolism by using 16alpha-[(18)F]fluoro-17beta-estradiol (FES) and fluorine 18 ((18)F) fluorodeoxyglucose (FDG) positron emission tomography (PET) in patients with benign and malignant uterine tumors. MATERIALS AND METHODS The institutional review(More)