Tetsuya Torio

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SKELETAL ADAPTATION TO MECHANICAL STRAIN IN HUMANS Several lines of clinical evidence (1–3) suggest that the adult skeleton in humans continuously responds to change in mechanical environment to maintain resultant “elastic” deformation (strain) of bone; increased or decreased bone strain would normally induce bone gain or loss, respectively. Indeed,(More)
In addition to other chronic diseases such as hypertension, hypercholesterolemia, and diabetes, a treat-to-target strategy was recently applied in rheumatoid arthritis and has now been discussed in osteoporosis. An important goal of osteoporosis therapy is normal risk of hip fracture associated with significant morbidity and mortality, but the anti-fracture(More)
Blunt cerebrovascular injury (BCVI) is known to be a potentially fatal complication of cervical spine injury (CSI). Methods for screening the appropriate population remain to be elucidated, especially in Japan. This retrospective study was conducted to predict the risk factors relevant to BCVIs. Among 92 patients with CSI transferred to our institution from(More)
Dear Editor, The latest meta-analysis of observational studies regarding the association between proton pump inhibitors (PPIs) and fracture risk by Zhou and colleagues [1] showed that PPI therapy was linked to an increased incidence of hip fracture (15 studies; relative risk 1.26, 95% confidence interval 1.16 to 1.36), vertebral fracture (4 studies; 1.58,(More)
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