Tetsuya Fujimoto

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Perinatal exposure to bisphenol A (BPA, 0.1 and 1 ppm in drinking water applied to mother rats for 6 weeks) has been shown to impair the sexual differentiation in exploratory behavior, but the exact critical period of this disrupting effect is still unknown. In this study, we examined the effects of prenatal exposure to BPA (0.1 ppm in drinking water(More)
In this paper, we proposed a soft-error hardened latch (SEH-latch) scheme that has an error correction function in the fine process. To achieve this, we designed two types of SEH-latch circuits and a standard latch circuit using 130 nm 2-well, and also 90 nm 2-well CMOS processes. The proposed circuit demonstrated 2-order higher immunity through a radiation(More)
HYPOTHESIS Assessment of whether elevation and lowering of the dominant and nondominant arms occur in a similar manner in healthy individuals is clinically important in terms of shoulder disorders. MATERIALS AND METHODS We examined the scapulohumeral rhythm (SHR) and performed electromyography (EMG) for the middle deltoid, upper trapezius, lower(More)
Bisphenol A (BPA) is one of the 'environmental endocrine disrupters' (EEDs) released by plastics and resin known to interfere with hormonal responses. In this study, female Wistar rats were exposed to low-dose BPA (24 μg/kg/day) during 7 days after giving birth. The male and female offspring, exposed to the BPA through lactation, were evaluated using an(More)
Hepatocyte spheroids are expected to be the main component of the artificial liver bioreactor for their higher function. The preparation of hepatocyte spheroids, however, can require as many as 24 to 96 h. To reduce this time, we investigated a method employing a new technique of rat hepatocyte preparation and a dynamic culture. The modified Seglen's method(More)
The oxidation behavior of Y-931, a potent atypical antipsychotic drug, was compared with that of clozapine and olanzapine. In two enzymatic systems (horseradish peroxidase (HRP)/glutathione (GSH) and HRP/H(2)O(2)/GSH) which generate thiyl radicals, clozapine markedly strengthened the electron paramagnetic resonance (EPR) signal for the radical. Olanzapine,(More)
Periodontal infections can increase patients' serum C-reactive protein (CRP) level, which is a predictive marker of future cardiovascular events. Serum CRP may be a key mediator associating periodontitis with cardiovascular disease. It is not yet clarified whether the chemotactic activity of monocytes changes with increased serum CRP. This study(More)
[Purpose] This study aimed to clarify the effects of therapeutic ultrasound on range of motion and stretch pain and the relationships between the effects. [Subjects] The subjects were 15 healthy males. [Methods] Subjects performed all three interventions: (1) ultrasound (US group), (2) without powered ultrasound (placebo group), and (3) rest (control(More)
PURPOSE This study aimed to clarify the effects of therapeutic ultrasound on intramuscular local blood circulation (and oxygen dynamics) using near-infrared spectroscopy (NIRS). PARTICIPANTS The participants were 11 healthy males. METHODS All participants performed all three trials; (1) the ultrasound (US group), (2) without powered ultrasound (placebo(More)