Tetsuro Araki

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During the past two years, significant progress has been made towards understanding the molecular basis of how multiple pathways regulating the floral transition are integrated. The transcriptional regulation of several genes, the floral meristem identity gene LEAFY and the 'flowering-time' genes FLOWERING LOCUS T and SUPPRESSOR OF OVEREXPRESSION OF CO 1(More)
BACKGROUND A common promoter polymorphism (rs35705950) in MUC5B, the gene encoding mucin 5B, is associated with idiopathic pulmonary fibrosis. It is not known whether this polymorphism is associated with interstitial lung disease in the general population. METHODS We performed a blinded assessment of interstitial lung abnormalities detected in 2633(More)
We report the imaging findings of metanephric adenoma. US examination showed a protruding hypoechoic mass at the right kidney. CT revealed a well defined isodense mass with calcifications. On angiography, neither neovascularization nor tumor staining was revealed at all. The T1-weighted MR images showed a hypointense mass that was slightly hyperintense on(More)
OBJECTIVE Interstitial lung diseases are associated with increased risk of lung cancer. The prevalence of ILA at diagnosis of advanced non-small-cell lung cancer (NSCLC) and its impact on overall survival (OS) remain to be investigated. MATERIALS AND METHOD The study included 120 treatment-naïve stage IV NSCLC patients (53 males, 67 females). ILA was(More)
OBJECTIVE The purpose of this article is to investigate the imaging characteristics of pathologically proven thymic hyperplasia and to identify features that can differentiate true hyperplasia from lymphoid hyperplasia. MATERIALS AND METHODS Thirty-one patients (nine men and 22 women; age range, 20-68 years) with pathologically confirmed thymic(More)
RATIONALE Galectin-3 (Gal-3) has been implicated in the development of pulmonary fibrosis in experimental studies, and Gal-3 levels have been found to be elevated in small studies of human pulmonary fibrosis. OBJECTIVES We sought to study whether circulating Gal-3 concentrations are elevated early in the course of pulmonary fibrosis. METHODS We examined(More)
Leukemic involvement of the kidney was demonstrated by computed tomography in five children. The findings were bilateral diffuse nephromegaly (2), unilateral diffuse nephromegaly (1), discrete intrarenal mass lesion (1), and a hilar mass lesion (1). In three children undergoing local radiation therapy, the leukemic kidneys responded well to treatment.(More)
Background: To elucidate the imaging characteristics of well-differentiated hepatocellular carcinomas (HCCs) on ultrasonography (US), computed tomography (CT), and magnetic resonance (MR) imaging. Methods: Ultrasonograms, CTs, and MR images of 18 histopathologically proven well-differentiated HCCs in 15 patients were reviewed. The findings of these images(More)
IMPORTANCE Interstitial lung abnormalities have been associated with lower 6-minute walk distance, diffusion capacity for carbon monoxide, and total lung capacity. However, to our knowledge, an association with mortality has not been previously investigated. OBJECTIVE To investigate whether interstitial lung abnormalities are associated with increased(More)
RATIONALE The relationship between the development and/or progression of interstitial lung abnormalities (ILA) and clinical outcomes has not been previously investigated. OBJECTIVES To determine the risk factors for, and the clinical consequences of, having ILA progression in participants from the Framingham Heart Study. METHODS ILA were assessed in(More)