Tetsuji Fujita

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OBJECTIVE To evaluate the safety and effectiveness of laparoscopic total gastrectomy with D2 lymphadenectomy for gastric cancer. DESIGN Review of findings from a prospectively acquired institutional database. SETTING University hospital. PATIENTS Fifty-five consecutive patients operated on by the same surgeon between October 1997 and March 2008. (More)
Although glutamine is an important fuel for the intestinal epithelium, the metabolic fate of glutamine extracted by the human intestine remains unclear. The aim of this study was to investigate the relationship between glutamine extraction and the release of other amino acids by the human intestine. In 21 patients undergoing major abdominal cancer surgery,(More)
Retraction of the liver is necessary to ensure an adequate working space in laparoscopic surgery, but the retraction force applied may cause transient liver dysfunction. We have introduced the technique using a Penrose drain to suspend the liver with the performance of laparoscopic gastrectomy for gastric adenocarcinoma. 111 patients with gastric(More)
BACKGROUND Percutaneous endoscopic gastrostomy (PEG) has become an important modality to provide enteral access for long-term nutritional support. Nevertheless, aspiration of liquid nutrients due to vomiting and reflux esophagitis caused by gastroesophageal reflux (GER) is a significant problem associated with tube feeding by PEG. MATERIALS AND METHODS(More)
BACKGROUND Tetracyclines such as doxycycline are reported to possess cytotoxic activity against mammalian tumor cells, but the mechanism of their effects on cell proliferation remains unclear. MATERIALS AND METHODS The antitumor effect of doxycycline was investigated in human pancreatic cancer cell line, PANC-1. We also investigated the effect of(More)
BACKGROUND Although depression is a predominant health care problem, it is difficult to diagnose in patients who underwent abdominal cancer surgery. Relevance of elevated levels of serum of alpha-2-macroglobulin (A2M) to psychological depression has been recently suggested. PATIENTS AND METHODS Serum A2M levels were measured and depression scores were(More)
Editor—In Wellwood et al’s trial of laparoscopic hernia repair versus open mesh repair only patients fit for general anaesthesia were preselected. We do not know if the rejected patients were suitable for local anaesthesia, which is usually ideal for frail and elderly patients and those with high American Society of Anesthesiologists grades. The type of(More)
Prospective multicenter trials have shown the feasibility of sentinel node (SN) navigation surgery using a dual tracer of dye and radioisotope for early gastric cancer. However, comparable trials using the indocyanine green (ICG) and the infrared ray laparoscopic system (IRLS) have not been reported. On the basis of our cohort studies, we assumed that the(More)