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Bone‐Staining Technique for Fetal Rat Specimens without Skinning and Removing Adipose Tissue
Abstract: A rapid procedure was developed for staining fetal rat specimens. Full‐term rat fetuses were fixed in 99% ethanol and only thoracoabdominal organs were removed. Without skinning andExpand
Species Difference in Developmental Toxicity of an N‐Phenylimide Herbicide between Rats and Rabbits and Sensitive Period of the Toxicity to Rat Embryos
It is likely that there is a common mechanism for the three types of developmental toxicity and that S‐53482 does not produce VSD by its direct damage to embryonic heart tissue. Expand
Close link between protoporphyrin IX accumulation and developmental toxicity induced by N-phenylimide herbicides in rats.
The peak period of PPIX accumulation corresponded to that of developmental effects, suggesting a close link between PPO inhibition and developmental abnormality. Expand
Dermal developmental toxicity of N-phenylimide herbicides in rats.
Dermal exposure of rats to S-53482 and S-23121 produced patterns of developmental toxicity similar to those resulting from oral exposure as well as teratogenic when administered dermally to pregnant rats as were the compounds administered orally. Expand
Difference in developmental toxicity among structurally similar N-phenylimide herbicides in rats and rabbits.
The mechanism of action of developmental toxicity by S-53482 should account for the compound-specific difference as well as species difference between rats and rabbits and the difference in developmental toxicity in rats was striking among N-phenylimide herbicides. Expand