Terukazu Kato

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Several beta-secretase inhibitors were designed based on hydroxyethylamine dipeptide isostere (HDI) structures and were synthesized by a methodology using the aza-Payne rearragement and O,N-acyl transfer reactions to study their structure-activity relationships. Among these pseudopeptides, effective compounds were developed as the first beta-secretase(More)
A self-oscillating gel is a system that generates an autonomous volume oscillation. This oscillation is powered by the chemical energy of the Belousov-Zhabotinsky (BZ) reaction, which demonstrates metal ion redox oscillation. A self-oscillating gel is composed of Poly-N-isopropylacrylamide (PNIPAAm) with a metal ion. In this study, we found that the(More)
Many types of stimuli-sensitive gels have been studied and applied to soft actuators with the progress of the functional materials. Especially, electro-active polymer gels seem to be promising. In all cases, however, the mechanical motion is powered by electric stimuli. Herein we show the self-susteined gel actuator driven by chemical energy. The polymer(More)
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