Teruaki Okushima

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We treated two patients with chronic inflammatory demyelinating polyneuropathy (CIDP) with high-dose intravenous immunoglobulin (HIG). The patients received 400 mg/kg of immunoglobulin a day for five days. One patient, who had failed to respond to prednisolone before, was treated with HIG, 18 months after the onset. His motor symptoms resolved immediately(More)
We report a 66-year-old woman clinically diagnosed as having a corticobasal degeneration (CBD), who showed electrophysiologically cortical reflex myoclonus. She developed a clumsiness and action myoclonus on the right extremities, and aphasia. The extrapyramidal signs such as dystonia and rigidity were also noted on the right side. Sequential MR images(More)
We analyze the dynamics of structural transitions between normal right-handed B form and unusual left-handed Z form for a linear DNA molecule. The dynamics under the external torque in physiological buffer is modeled by a Langevin equation, with the potential term given by the authors previously [Phys. Rev. E 84, 021926 (2011)]. With this model, we first(More)
A dynamical model is presented for chiral change in DNA molecules. The model is an extension of the conventional elastic model, which incorporates the structure of base pairs and uses a spinor representation for the DNA configuration together with a gauge principle. Motivated by a recent experiment reporting chiral transitions between right-handed B-DNA and(More)
A mapping called a connectivity graph is proposed to visualize the complicated networks between local minima via saddles on many-dimensional potential energy surfaces. With this mapping, the effect of the topography of a complex potential energy surface on the dynamics is studied in model funnel potentials and a Lennard-Jones cluster. We present strong(More)
Using microscopic models in which both photons and excitons are treated as microscopic degrees of freedom, we discuss polaritons of two cases: One is the case when excitonic parameters are time dependent. The time dependence causes creation of polaritons from a " false vacuum. " It is shown that both the creation sepctra and the creation efficiency are much(More)
Following flu-like illness a 75 year old man developed pure sensory neuropathy that reached a peak at 3 weeks. Cerebrospinal fluid protein was elevated with no increase in cell count The sensory deficits started to improve 4 months later, and were completely resolved 12 months later. Compound sensory nerve action potential, which had been absent initially,(More)
A 9 year old boy had chronic progressive motor-sensory neuropathy that started in early infancy. He had enlarged nerves and pes cavus deformity. Motor conduction studies showed very dispersed, polyphasic compound muscle action potentials with conduction velocities around 2 m/s. A sural nerve biopsy showed severe loss of myelinated fibres. Two months of(More)
We describe a 9-year-old boy with chronic inflammatory demyelinating polyneuropathy (CIDP), whose distal dominant, slowly progressive motor sensory involvement developed since infancy. Thickened peripheral nerves were visible in his neck and palpable in the extremities. The hand muscles were atrophic and both feet showed pes cavus deformity. He was unable(More)
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