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Two populations of blastomeres become positionally distinct during fourth cleavage in the mouse embryo; the inner cells become enclosed within the embryo and the outer cells form the enclosing layer. The segregation of these two cell populations is important for later development, because it represents the initial step in the divergence of placental and… (More)

A codon-based approach to estimating the number of variable sites in a protein is presented. When first and second positions of codons are assumed to be replacement positions, a capture-recapture model can be used to estimate the number of variable codons from every pair of homologous and aligned sequences. The capture-recapture estimate is compared to a… (More)

- Peter Aronow, Winston Lin, Terry Speed, Jonathan, Candidate
- 2011

Experimenters often use post-stratification to adjust estimates. Post-stratification is akin to blocking, except that the number of treated units in each stratum is a random variable because stratification occurs after treatment assignment. We analyze both post-stratification and blocking under the Neyman-Rubin model and compare the efficiency of these… (More)

A clone map of part or all of a chromosome is the result of organizing order and overlap information concerning collections of DNA fragments called clone libraries. In this paper the expected amount of information Ž. entropy needed to create such a map is discussed. A number of different formalizations of the notion of a clone map are considered, and exact… (More)

- N Petrov, F Cs, Akademiai Budapest, N Kiado, M Merhav, Feder +5 others
- 2010

215 Because the last expression is independent of k or T * , its negative logarithm is a lower bound on I (p m) , that is I (~ ~) 2-E ~ * iog~re-" /4.H2(f " f7,) = m log2-m log (1 + e-fcm) Choosing m = An1/(' " +') (A > 0) to maximize the rate in the above lower bound, we get the following theorem. Taking k = 0, Y = 1 therefore s = 1 in the theorem, we… (More)

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