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Imaging genetics combines brain imaging and genetics to detect genetic variation in brain structure and function related to behavioral traits, including psychiatric endpoints, cognition, and affective regulation. This special issue features extensive reviews of the current state-of-the-art of the field and adds new findings from twin and candidate gene(More)
Working memory (WM) has been described as short-term retention of information that is no longer accessible in the environment, and the manipulation of this information for subsequent use in guiding behavior. WM is viewed as a cognitive process underlying higher-order cognitive functions. Evidence supports a critical role for PFC in mediating WM performance.(More)
INTRODUCTION In patients with severe mental disorders outcome measurement should include symptoms, cognition, functioning and quality of life at least. Shorter and efficient instruments have greater potential for pragmatic and valid clinical utility. Our aim was to develop the Spanish UPSA Brief scale (Sp-UPSA-Brief). MATERIAL AND METHODS Naturalistic,(More)
Mortality among adolescents resident in the municipal district of Botucatu, State of S. Paulo, Brazil, according to age group (10 to 14 and 15 to 19 years), sex, occupation and cause of death, during the period from 1984 to 1993, was analysed. The mortality data were obtained from death certificates and the population estimates were based upon census(More)
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