Terrence E. Turner

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Intelligent Tutoring Systems are notoriously costly to construct [1], and require PhD level experience in cognitive science and rule based programming. The goal of this research was to ease the development process for building pseudo-tutors [4], which are ITS constructs that mimic cognitive tutors but are limited in that they only work for a single problem.(More)
Middle school mathematics teachers are often forced to choose between assisting students' development and assessing students' abilities because of limited classroom time available. To help teachers make better use of their time, a web-based system, called the Assistment system, was created to integrate assistance and assessment by offering instruction to(More)
Intercellular adhesion molecule 5 (ICAM-5, telencephalin) is a cell adhesion molecule expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon. Antibody studies in rodents and rabbits have demonstrated expression of this molecule on the cell body and dendrites of these neurons. We have examined the expression pattern in(More)
Although there is no doubt about the influence of the genetic background in the onset of the allergic diseases, Epigenome-Wide Association Studies are needed to elucidate the possible relationship between allergic diseases and epigenomic dysregulation. In this study we aimed to analyze the epigenetic patterns, in terms of DNA methylation, of three(More)
Intercellular adhesion molecule (ICAM)-5 (telencephalin) is unique among the ICAMs, because it is only expressed in somatodendritic membranes of telencephalic neurons. To investigate the fate of ICAM-5 during focal brain injury, we induced hypoxia-ischemia (HI) damage in adult mice by right common carotid artery ligation followed by hypoxia. ICAM-5 was(More)
Middle school mathematics teachers are often forced to choose between assisting students' development and assessing students' abilities because of limited classroom time available. To help teachers make better use of their time, we are integrating assistance and assessment by utilizing a web-based system ("Assistment") that will offer instruction to(More)
Intelligent Tutoring Systems, while effective at producing student learning [2,7], are notoriously costly to construct [1,9], and require PhD level experience in cognitive science and rule based programming. The literature suggests [1,9] that it takes at least 200 hours of work to build 1 hour on ITS content. We have been engaged in building tools to reduce(More)
We have analyzed in detail the precise requirements for the induction of human IgE synthesis using several experimental approaches with purified B cells and well-characterized alloantigen-specific CD4+ T cell clones expressing different profiles of lymphokine secretion. Using these clones under cognate conditions in which the B cells expressed alloantigens(More)
A series of murine erythroleukemia cell (MELC) variants was generated by selection for the ability to grow in increasing concentrations of the folate antagonist methotrexate (MTX). Growth of the parental MELC strain DS-19 was completely inhibited by 0.1 microM MTX. We isolated cells able to grow in 5, 40, 200, 400, and 800 microM MTX. Growth rates and(More)
Thrombospondin-1 (TSP-1) is a glycoprotein that plays a role in extracellular matrix (ECM) remodeling. Previously, we have shown that multiwalled carbon nanotubes (MWCNT) regulate ECM components TGFβ and its target Col3A1 in alveolar epithelial cells. In this study, we investigated the effect of MWCNT on TSP-1 and microRNA-1 (miR-1) in the regulation of(More)
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