Teresinha Gonçalves-Silva

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Non-steroidal anti-inflammatory drugs (NSAIDs) represent a group of approximately 50 different medicines that are widely prescribed for the management of inflammation and that exhibit variable anti-inflammatory, anti-pyretic and analgesic activities. Most NSAIDs also exhibit a shared set of adverse effects, particularly related to gastrointestinal(More)
José Marcílio Sobral Cavalcante, Tiago Bezerra de Sá de Souza Nogueira, Anna Cláudia de Andrade Tomaz, Davi Antas e Silva, Maria de Fátima Agra e Maria de Fátima Vanderlei de Souza* Laboratório de Tecnologia Farmacêutica “Prof. Delby Fernandes de Medeiros”, Centro de Ciências da Saúde, Universidade Federal da Paraíba, CP 5009, 58051-970 João Pessoa PB,(More)
A series of 2-[(arylidene)amino]-cycloalkyl[b]thiophene-3-carbonitriles (2a-x) was synthesized by incorporation of substituted aromatic aldehydes in Gewald adducts (1a-c). The title compounds were screened for their antifungal activity against Candida krusei and Criptococcus neoformans and for their antiproliferative activity against a panel of 3 human(More)
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