Teresa Ptaszynska

Learn More
Ankylosing spondylitis (AS) is a potentially disabling rheumatic disease for which no curative treatment has yet been discovered. An extensive computer-based and manual search was undertaken to evaluate the role of microbes in the pathogenesis of AS. All together 147 papers were scrutinised. A total of 24 studies carried out on 1330 AS patients and 1191(More)
Antibodies to Klebsiella, but not to other bacteria, have been shown to be present in patients with active ankylosing spondylitis (AS) by seven different techniques. Antibodies to Proteus, but not to E. coli or Klebsiella, have been shown to be present in patients with active rheumatoid arthritis (RA) by three different techniques. It is suggested AS and RA(More)
The association between HLA-B27 and ankylosing spondylitis could be explained by a "crosstolerance hypothesis". Experimental studies demonstrate immunological crossreactivity between HLA-B27 and antigens found in Gram-negative bacteria, such as Klebsiella. Clinical studies show that an increased frequency of patients with ankylosing spondylitis and uveitis(More)
Antibodies to proteus species were measured in patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS) and in healthy controls by a Coombs agglutination method. The titres to Proteus mirabilis were higher in 30 RA patients being treated with gold than in 24 patients with active AS (p less than 0.001), 28 patients with inactive AS (p less(More)
OBJECTIVE To assess the tolerance to and patient acceptability of a placebo intravaginal ring in hysterectomized, postmenopausal women over a 28-day period. DESIGN Open, single-center. SETTING University hospital specialist menopause clinic. PARTICIPANTS A total of 24 healthy postmenopausal women attending menopause clinics at King's College Hospital(More)
  • 1