Terence Ball

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OBJECTIVE To determine the efficacy, tolerability, and safety of duloxetine when added to oral nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with osteoarthritis (OA) of the knee with pain of moderate or greater severity. RESEARCH DESIGN AND METHODS This was a 10-week randomized, double-blind, flexible-dose (duloxetine 60/120 mg/day),(More)
To evaluate whether hypoxia-induced increases in adrenal cortical (CQ) and medullary (MQ) blood flow (radiolabeled microspheres) occur secondary to hypoxia-induced secretory activity, pentobarbital-anesthetized ventilated dogs were pretreated with dexamethasone (DEX) to prevent adrenocorticotropic hormone (ACTH) and corticosteroid secretory changes or(More)
Spinal ischemia with resultant cord infarction is a catastrophic complication of surgical procedures involving the thoracoabdominal aorta. A rabbit spinal ischemia model was used to test if glucose administration would increase neurologic deficit of the lower extremity. Rabbits (2 to 3 kg), anesthesized with halothane, had a snare occluder placed around the(More)
The antioxidant lodoxamide tromethamine was assessed for effects on experimental spinal cord ischemia in the rabbit. Lodoxamide (20 mg/kg/hr) or 0.9% sodium chloride was infused beginning 15 minutes before infrarenal aortic occlusion and continuing for 105 minutes. With an occlusion time of 20 minutes, eight of eight lodoxamide-treated animals and five of(More)
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