Teodor Silviu Balaban

Learn More
Magic angle spinning (MAS) NMR dipolar correlation spectroscopy was applied for the first time to a biologically intact system, the light-harvesting chlorosomes of the green photosynthetic bacterium Chlorobium tepidum. The MAS spectra provide evidence that the self-organization of many thousands of bacteriochlorophyll c (BChl c) molecules is the predominant(More)
Immune tolerance to beta-amyloid (Abeta) was broken in NORBA transgenic mice presenting Abeta plaques on their pancreases. Vaccination of Black C57, BALB/c, and NORBA mice with the synthetic Abeta(1-16) sequence modified by covalently attaching two palmitoyl residues at each end of the peptide, subsequently reconstituted in liposomes-Lipid A elicited titers(More)
The central magnesium (Mg) atoms of natural occurring tetrapyrroles such as chlorophylls (Chls) and bacteriochlorophylls (BChls) are typically five-coordinated, a fact which leads to the formation of diastereoisomers if the Mg-ligand bond is stable on the time scale of the observation method. This possibility has only been briefly addressed before in a(More)
A recent study of the stereochemical details of chlorophyll ligation in photosystem I [Balaban et al., Biochim. Biophys. Acta 1556 (2002) 197-207] has revealed that only 14 chlorophylls out of the total 96 are ligated from the same side (syn) as the 17-propionic acid residue which is esterified with phytol. The syn chlorophylls are carefully surrounding the(More)
Binuclear square planar Ni(II) complexes are described, formed by two tridentate ligands with two imine-nitrogens coordinating two nickel atoms. Such complexes are synthetically readily available with great structural variety and present new types of ridge-tile-like chiral compounds that are reasonably stable in the appropriate "bent" conformation.(More)
There is much diversity in the way in which photosynthetic organisms harvest sunlight. In chromophore-protein complexes, an exact orientation of pigments by the protein matrix ensures an efficient stepwise energy transfer to the reaction center where charge separation occurs. The charge separation and subsequent electron transfer steps are, however, very(More)
Bacteriochlorophylls (BChls) c, d, and e are the main light-harvesting pigments of green photosynthetic bacteria that self-assemble into nanostructures within the chlorosomes forming the most efficient antennas of photosynthetic organisms. All previous models of the chlorosomal antennae, which are quite controversially discussed because no single crystals(More)
Annemarie Huijser,† Peter L. Marek,‡,| Tom J. Savenije,† Laurens D.A. Siebbeles,† Torsten Scherer,‡ Robert Hauschild,§ Jȩdrzej Szmytkowski,§ Heinz Kalt,§ Horst Hahn,‡,| and Teodor Silviu Balaban*,‡ Opto-Electronic Materials Section, DelftChemTech, Delft UniVersity of Technology, Julianalaan 136, 2628 BL, Delft, The Netherlands, Karlsruhe Institute of(More)
The recent high-resolution crystal structure of LHC II [Liu et al. (2004) Nature 428: 287–292] makes possible an unprecedented insight into the stereochemical features of how chlorophylls (Chl)s are bound. The diastereotopic ligation generates four structurally different pigment types, two Chl a and two Chl b, which are distinguished not only by the groups(More)
Diacylation of copper 10,20-bis(3,5-di-tert-butylphenylporphyrin) using Friedel-Crafts conditions at short reaction times, high concentrations of catalyst, and 0-4 degrees C affords only the 3,17-diacyl-substituted porphyrins, out of the 12 possible regioisomers. At longer reaction times and higher temperatures, the 3,13-diacyl compounds are also formed,(More)