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—Automated scene analysis has been a topic of great interest in computer vision and cognitive science. Recently, with the growth of crowd phenomena in the real world, crowded scene analysis has attracted much attention. However, the visual occlusions and ambiguities in crowded scenes, as well as the complex behaviors and scene semantics, make the analysis a(More)
As the most rigid cytoskeletal filaments, microtubules bear compressive forces in living cells, balancing the tensile forces within the cytoskeleton to maintain the cell shape. It is often observed that, in living cells, microtubules under compression severely buckle into short wavelengths. By contrast, when compressed, isolated microtubules in vitro buckle(More)
This paper presents a source localization algorithm based on the source signal's time-of-arrival (TOA) at sensors that are not synchronized with one another or the source. The proposed algorithm estimates source positions using a window of TOA measurements which, in effect, creates a virtual sensor array. Based on a Gaussian noise model, maximum likelihood(More)
DNA methylation patterns are initiated by de novo DNA methyltransferases DNMT3a/3b adding methyl groups to CG dinucleotides in the hypomethylated genome of early embryos. These patterns are faithfully maintained by DNMT1 during DNA replication to ensure epigenetic inheritance across generations. However, this two-step model is based on limited data. We(More)
Von Hippel-Lindau (VHL) disease is an autosomal dominant familial cancer syndrome caused by germline mutations in VHL tumor suppressor gene. It is characterized by hemangioblastoma in central nervous system and retina, renal cell carcinoma or cyst, pheochromocytoma, pancreatic cyst and tumor, endolymphatic-sac tumor, and papillary cystadenoma in epididymis(More)
—Conventional semi-supervised image annotation algorithms usually propagate labels predominantly via holistic similarities over image representations, and do not fully consider the label locality, inter-label similarity, and intra-label diversity among multi-labelimages. Taking these problems into consideration , we present the hidden-concept driven image(More)
The malleable nature of atomically thin graphene makes it a potential candidate material for nanoscale origami, a promising bottom-up nanomanufacturing approach to fabricating nanobuilding blocks of desirable shapes. The success of graphene origami hinges upon precise and facile control of graphene morphology, which still remains as a significant challenge.(More)
The incorporation of GPUs as co-processors has brought forth significant performance improvements for High-Performance Computing (HPC). Efficient utilization of the GPU resources is thus an important consideration for computer scientists. In order to obtain the required performance while limiting the energy consumption, researchers and vendors alike are(More)
Aneuploidy and chromosomal instability are major characteristics of human cancer. These abnormalities can result from defects in the spindle assembly checkpoint (SAC), which is a surveillance mechanism for accurate chromosome segregation through restraint of the activity of the anaphase-promoting complex/cyclosome (APC/C). Here, we show that a(More)