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Viral oncoproteins E6/E7 play key oncogenic role in human papillomavirus (HPV)-mediated cervical carcinogenesis in conjunction with aberrant activation of cellular signaling events. GLI-signaling has been implicated in metastasis and tumor recurrence of cervical cancer. However, the interaction of GLI-signaling with HPV oncogenes is unknown. We examined(More)
Etiological role of viral proteins E6 and E7 of high-risk HPV in cervical carcinogenesis is well established. However, their contribution in chemoresistance and epithelial-mesenchymal transition (EMT) that leads to advanced metastatic lesions and chemoresistance is poorly defined. In the present study, contribution of viral oncoproteins in acquisition of(More)
To study the visual air quality of Delhi, size fractionated aerosols - coarse and fine fractions of PM10 - were collected and analysed for SO4(-2), NO(-3), NH4+ and EC at three sites with different background activities. The analysed species constitute a smaller portion of coarse fraction (39%) but a larger portion of fine fraction (69%). The sampling was(More)
Prior studies established constitutively active AP-1, NF-κB, and STAT3 signaling in oral cancer. Differential expression/activation of specific members of these transcription factors has been documented in HPV-positive oral lesions that respond better to therapy. We performed a comprehensive analysis of differentially expressed, transcriptionally active(More)
Lymphatic filariasis is a major public health problem of tropical countries. Although its elimination is planned as global effort using mass drug administration in affected communities but its impact has been influenced by MDA coverage across countries. The drug coverage is affected by fever as side effect and its continuation for over 6 years which affect(More)
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