Tegan S Darch

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BACKGROUND A routine pediatric clinical assessment of body composition is increasingly recommended but has long been hampered by the following 2 factors: a lack of appropriate techniques and a lack of reference data with which to interpret individual measurements. Several techniques have become available, but reference data are needed. OBJECTIVE We aimed(More)
Adolescent obesity is difficult to assess in multi-ethnic populations using BMI, due to variability in the BMI-fatness relationship. We aimed to describe body composition (BC), and to validate leg-leg bioelectrical impedance analysis (BIA), in adolescents from different ethnic groups using deuterium (D(2)O) as the reference method. Measurements were made of(More)
Decrease in fat mass (FM) is a one of the aims of pediatric obesity treatment; however, measurement techniques suitable for routine clinical assessment are lacking. The objective of this study was to validate whole-body bioelectrical impedance analysis (BIA; TANITA BC-418MA) against the three-component (3C) model of body composition in obese children and(More)
BACKGROUND Hydrometry and densitometry are widely used to assess pediatric body composition due to their ease of application. The accuracy of these techniques depends on the validity of age- and sex-specific constant values for lean tissue hydration or density. Empirical data on these constants, and their variability between individuals, are lacking. (More)
BACKGROUND Malnutrition in late infancy in developing countries may result from poor-quality complementary foods that displace breast milk. OBJECTIVE The objective of the study was to assess the effects of fortified complementary blends of different energy densities on growth, hemoglobin concentrations, and breast milk intake of 9-mo-old Zambian infants.(More)
BACKGROUND Body composition is increasingly measured in pediatric obese patients. Although dual-energy X-ray absorptiometry (DXA) is widely available, and is precise, its accuracy for body composition assessment in obese children remains untested. OBJECTIVE We aimed to evaluate DXA against the four-component (4C) model in obese children and adolescents in(More)
Gambian infants show growth faltering, but the underlying body composition is unknown. The present study aimed to compare body composition in Gambian and UK infants using 2H dilution; and to evaluate accuracy of bioelectrical impedance analysis (BIA) and creatinine excretion for estimating lean mass (LM), using 2H as the reference. Body composition was(More)
Deuterium (2H) in water and urine can be measured by off-line and, more recently, on-line techniques using isotope ratio mass spectrometry (IRMS). We describe a new simple on-line pyrolysis method for the analysis of 2H/1H in water and urine samples by continuous flow IRMS, normally used for 2H/1H measurements in organic compounds. A deactivated column(More)
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