Teerawat Monnor

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Aromatase, a rate-limiting enzyme catalyzing the conversion of androgen to estrogen, is overexpressed in human breast cancer tissue. Aromatase inhibitors (AIs) have been used for the treatment of estrogen-dependent breast cancer in post-menopausal women by blocking the biosynthesis of estrogen. The undesirable side effects in current AIs have called for(More)
BACKGROUND The aim of this study is to explore the relationship between hematological parameters and glycemic status in the establishment of quantitative population-health relationship (QPHR) model for identifying individuals with or without diabetes mellitus (DM). METHODS A cross-sectional investigation of 190 participants residing in Nakhon Pathom,(More)
This study represents the first large-scale study on the chemical space of inhibitors of dipeptidyl peptidase-4 (DPP4), which is a potential therapeutic protein target for the treatment of diabetes mellitus. Herein, a large set of 2,937 compounds evaluated for their ability to inhibit DPP4 was compiled from the literature. Molecular descriptors were(More)
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