Learn More
In a retrospective study, 31 patients were identified over a period of 25 years as having sustained traumatic knee dislocations without associated fractures. Three patients had early amputation secondary to vascular complications. Ten popliteal artery disruptions and five peroneal nerve palsies were diagnosed. At the time of follow-up evaluation (average,(More)
The evaluation of subglottic stenosis has been limited by the lack of standardized methods for determining the cross-sectional area and length of the stenotic segment. A rabbit model was used to prospectively evaluate the correlation between computed tomography (CT) and bronchoscopy in the evaluation of this disease. Subglottic stenosis was produced in 39(More)
A phase II pilot study of amsacrine in refractory adult acute leukemia was conducted by the Southeastern Cancer Study Group from May 1979 to August 1980. Amsacrine, 90 mg/m2, was given daily for 5-8 days to 45 patients with acute myeloblastic leukemia, 15 patients with acute lymphoblastic leukemia, and six patients with blastic transformation of chronic(More)
In a randomized study 115 postmenopausal women with advanced breast cancer who were estrogen receptor-unknown or -positive were treated initially with tamoxifen or diethylstilbestrol (DES). Their pretreatment characteristics showed no significant difference. The frequency of response was identical with tamoxifen and DES, showing a complete response rate of(More)
Kainic acid- and K+-evoked in vitro release of endogenous amino acids from hippocampal slices were measured in rats kindled by entorhinal electrical stimulation. One month after completion of kindling, K+-evoked release of glutamate from hippocampal slices ipsilateral to the stimulus site was consistently greater than from both the contralateral hippocampus(More)
Rats were kindled to two consecutive class 5 seizures by once-daily entorhinal electrical stimulation. After one stimulus-free month, in vitro Ca2(+)-dependent, K(+)-stimulated endogenous amino acid release was measured in regio superior, regio inferior and dentate gyrus of the hippocampal formation. Ca2(+)-dependent L-glutamate release was robust in all 3(More)
OBJECTIVES This study addresses the impact of stenting on early wound healing after laryngotracheal reconstruction (LTR) in a rabbit model with established subglottic stenosis. METHODS Subglottic stenosis was created in 42 New Zealand white rabbits through a transoral, endoscopic technique. Three weeks later, endoscopy and axial CT were performed to(More)
OBJECTIVE To study the effects of corticosteroids and fibroblast growth factor on composite graft survival using a rabbit model of auricular amputation and reimplantation. DESIGN Randomized, "blinded," placebo-controlled, prospective animal study. SETTING Animal laboratory in tertiary care center. INTERVENTION Amputation of the distal 2 cm of the(More)