Tayana Lapteva

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After ischemic stroke, cell damage propagates from infarct core to surrounding tissues (penumbra). To reveal proteins involved in neurodegeneration and neuroprotection in penumbra, we studied protein expression changes in 2-mm ring around the core of photothrombotic infarct induced in the rat brain cortex by local laser irradiation after administration of(More)
The activities of alanine and aspartate aminotransferases were assessed in the embryos and juveniles of the rainbow trout Parasalmo mykiss L. and chum salmon Oncorhynchus keta W. Changes in subcellular localization of these enzymes and their activities were found at different pH optima in each subcellular fraction of the rainbow trout during ontogenesis.
We studied the activities of the marker enzymes of physiological state and adaptive reactions, aspartate and alanine aminotransferases, in early development of the keta Oncorhynchus keta. Aspartate aminotransferase with pH optima 6.8, 7.0, 7.6, and 8.0 and alanine aminotransferase with pH optima 7.0, 7.4, 7.6, 7.8, 8.0, and 8.2 were found in the eggs,(More)
The effect of dalargin (D-AlaZ,LeuS,ArgB-enkephalin), a synthetic analog of Leu-enkephaiin, on animals and man is under active study at the present time. We know that dalargin has a marked protective and antistressor effect, that it affects the levels of ACTH, cortisone, and hormones of the pituitary-thyroid complex in the blood plasma and the cAMP(More)
After dalargin treatment of fish eggs (at the stage of swollen egg envelopes) and on juveniles (at the stage of early meiotic oocyte appearance in gonads) DNA content is observed to raise up to 85% and 66%, respectively in yearlings and up to 20% and 23% respectively in second-year fish as compared to the control ones. Dalargin also influences the exchange(More)
The hexapeptide dalargin (a synthetic analog of leu-enkephalin) injected in the hemolymph of bee moth (Galleria mellonella) and of mealworm (Tenebrio molitor) causes a dose-dependent increase in the DNA content and an increase in the3H-thymidine incorporation in DNA. In bee moth, the maximum (43–68%) increase in radioactivity is observed after injection of(More)
We studied the activities of the marker enzymes of physiological state and adaptive reactions, aspartate and alanine aminotransferases, in early development of the keta Oncorhynchus keta. Aspartate aminotransferase with pH optima 6.8, 7.0, 7.6, and 8.0 and alanine aminotransferase with pH optima 7.0, 7.4, 7.6, 7.8, 8.0, and 8.2 were found in the eggs,(More)
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