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Selenium (Se) is an exogenous antioxidant that performs its function via the expression of selenoproteins. The aim of this study was to explore the effect of varying Se intake on the redox status of the aortic wall in young spontaneously hypertensive rats (SHR). Sixteen male Wistar Kyoto (WKY) rats and nineteen male SHR, 16-week-old, were tested after being(More)
A 68-year-old female presented to the Gynecologic Oncology Clinic with a right-lower quadrant abdominal mass 3 × 4 cm in diameter palpable on pelvic examination. Her routine laboratory tests were normal. Transvaginal ultrasonography revealed a cystic mass in the right adnexa 3.9 cm in diameter, which was thought to arise in the ovary. At the time of(More)
PURPOSE Literature data suggest that investigation of the circumferential resection margin (CRM) in rectal cancer surgery gives significant information for prognosis of the disease and the quality of the performed operation. The aim of this study was to analyze the clinical and morphological aspects of CRM in pT3 tumors in relation to their significance for(More)
A methodic for pathologic handling and investigation of surgical resection specimen in rectal cancer is presented. It is conformed with recent trends of multidisciplinary approach to rectal cancer. Surgeon is involved in macroscopic investigation of the fresh specimen, whether pathologist is responsible for macroscopic and histological examination of the(More)
PURPOSE To evaluate the prognostic significance of 16 clinical, pathomorphological and immunohistochemical features for predicting distant metastasis (DM) and 5-year overall survival (OS) in breast cancer (BC) patients. PATIENTS AND METHODS A retrospective study of 378 patients with invasive BC (T1-3N0-3M0), who were operated between 2000 and 2003 at our(More)
Gastrointestinal Stromal Tumors (GISTs) are uncommon mesenchimal tumors that usually arise in the wall of the gastrointestinal tract. Although heterogenous in morphology, GISTs represent a group of tumors probably originating from the intestinal pacemaker cell, interstitial cell of Cajal. The tumour cell phenotype can be established only when(More)
Breast carcinoma is a heterogeneous disease. Clinical treatment of metastases from triple negative-Estrogen receptor-(ER(-), Progesterone receptor (PgR)(-), Human epidermal growth factor receptor 2(HER2)(-)) primary breast cancer and metachronous second cancer in visceral organs is different. In this article we report two cases of visceral metastases from(More)
Mammographic screening has led to increased detection of intraductal carcinoma of the breast (IdC). IdC is y heterogeneous disorder with different clinical outcomes. The study was designed to confirm consensibility of the three-tiered classification, accepted by Thomas Jefferson University Consensus Conference since 1997. The study population comprised 30(More)
UNLABELLED The aim of the present study was to investigate the effect of zinc on the activity of copper-zinc superoxide dismutase (Cu/Zn SOD), the lipid profile, the arterial blood pressure and the morphological changes of the aorta in male spontaneously hypertensive rats (SHR). MATERIALS AND METHODS The study included 52 male SHR animals. The animals(More)