Learn More
OBJECTIVE To investigate whether interleukin (IL)-6 or vascular endothelial growth factor (VEGF) influences macular edema in patients with central retinal vein occlusion (CRVO). DESIGN Retrospective case-control study. PARTICIPANTS Twenty-seven patients who had macular edema with CRVO and 16 patients with nonischemic ocular diseases (control group). (More)
PURPOSE To evaluate the association between vitreous inflammatory factors and the severity of diabetic macular edema (DME). DESIGN Retrospective case-control study. PARTICIPANTS Fifty-three patients with DME, 15 patients with nondiabetic ocular disease, and 8 diabetic patients without retinopathy. METHODS Vitreous fluid samples were obtained during(More)
PURPOSE To assess the relationship between age and the incidence and severity of conjunctivochalasis by using the grading system for conjunctivochalasis proposed by Meller and Tseng. DESIGN Prospective, nonrandomized, consecutive case study. METHODS A total of 1,416 patients aged one to 94 years were enrolled. The age, gender, medical history, ocular(More)
PURPOSE To isolate precursors of human corneal endothelial cells (HCECs) in vitro. METHODS HCECs were subjected to a sphere-forming assay in which spheres floated in serum-free medium containing growth factors. To promote differentiation, the isolated sphere colonies were plated in dishes coated with poly-L-lysine (PLL)/laminin or fetal bovine endothelium(More)
PURPOSE To evaluate the association between vitreous fluid levels of inflammatory factors and macular edema in patients with central retinal vein occlusion (CRVO). METHODS In 30 CRVO patients with macular edema and 29 controls with idiopathic macular hole, vitreous fluid samples were obtained during vitreoretinal surgery. Retinal ischemia was evaluated(More)
Human corneal endothelial cells (HCECs) have a limited proliferative capacity. Descemet stripping with automated endothelial keratoplasty (DSAEK) has become the preferred method for the treatment of corneal endothelial deficiency, but it requires a donor cornea. To overcome the shortage of donor corneas, transplantation of cultured HCEC sheets has been(More)
PURPOSE To evaluate the feasibility of a novel method of magnetic attraction of iron-endocytosed corneal endothelial cells to Descemet's membrane. METHODS Cultured rabbit corneal endothelial cells (RCEC) were exposed to spherical iron powder at various concentration ranging 0-100 micro moll(-1). After 24hr, the cell density and morphology were evaluated.(More)
PURPOSE To assess the relationship between apparent accommodation in pseudophakic eyes, multifocal corneal effects, and wavefront aberrations of the cornea. METHODS In 102 eyes of 86 patients who had undergone phacoemulsification and posterior chamber intraocular lens implantation, the amount of apparent accommodation was measured with an accommodometer.(More)
PURPOSE Aqueous levels of vascular endothelial growth factor (VEGF) and interleukin-6 (IL-6) are associated with the severity of macular edema in patients with central retinal vein occlusion (CRVO). We investigated whether aqueous and vitreous levels of these molecules were correlated in CRVO patients. METHODS Aqueous and vitreous samples were obtained(More)
OBJECTIVE Exposure to particulate matter less than 2.5 μm in diameter (PM2.5) is associated with asthma and respiratory symptoms, but little is known about the influence of PM2.5 on allergic conjunctivitis. The purpose of this study was to examine the association of PM2.5 with outpatient attendance for allergic conjunctivitis. METHODS We conducted a(More)