Tatsuya Haga

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Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

Kazuko Haga, Andrew C Kruse, +8 authors Takuya Kobayashi
Nature
2012

The parasympathetic branch of the autonomic nervous system regulates the activity of multiple organ systems. Muscarinic receptors are G-protein-coupled receptors that mediate the response to… (More)

Molecular bases of odor discrimination: Reconstitution of olfactory receptors that recognize overlapping sets of odorants.

Kazuki Kajiya, Koichiro Inaki, Masaki Tanaka, Tatsuya Haga, Hiroshi Kataoka, Kazushige Touhara
The Journal of neuroscience : the official…
2001

The vertebrate olfactory system discriminates a wide variety of odorants by relaying coded information from olfactory sensory neurons in the olfactory epithelium to olfactory cortical areas of the… (More)

Choline uptake systems of rat brain synaptosomes.

Tatsuya Haga, Hisayo Noda
Biochimica et biophysica acta
1973

Identification of G protein-coupled receptor genes from the human genome sequence.

Shigeki Takeda, Shiro Kadowaki, Tatsuya Haga, Hirotomo Takaesu, Shigeki Mitaku
FEBS letters
2002

We have identified novel G protein-coupled receptors (GPCRs) with no introns in the coding region from the human genome sequence: 322 olfactory receptors; 22 taste receptors; 128 registered GPCRs for… (More)

Identification and characterization of the high-affinity choline transporter

Takashi Okuda, Tatsuya Haga, Yoshikatsu Kanai, Hitoshi Endou, Takeshi Ishihara, Isao Katsura
Nature Neuroscience
2000

In cholinergic neurons, high-affinity choline uptake in presynaptic terminals is the rate-limiting step in acetylcholine synthesis. Using information provided by the Caenorhabditis elegans Genome… (More)

Internalization and down-regulation of human muscarinic acetylcholine receptor m2 subtypes. Role of third intracellular m2 loop and G protein-coupled receptor kinase 2.

Hirofumi Tsuga, Kimihiko Kameyama, Tatsuya Haga, Takenori Honma, Jelveh Lameh, Wolfgang Sadee
The Journal of biological chemistry
1998

Internalization and down-regulation of human muscarinic acetylcholine m2 receptors (hm2 receptors) and a hm2 receptor mutant lacking a central part of the third intracellular loop (I3-del m2… (More)

Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate.

Takashi Okuda, Michiko Okamura, China Kaitsuka, Tatsuya Haga, David Gurwitz
The Journal of biological chemistry
2002

High affinity choline uptake plays a critical role in the regulation of acetylcholine synthesis in cholinergic neurons. Recently, we succeeded in molecular cloning of the high affinity choline… (More)

Sequestration of dopamine D2 receptors depends on coexpression of G-protein-coupled receptor kinases 2 or 5.

Ken R. Ito, Tatsuya Haga, J Lameh, Wolfgang Sadee
European journal of biochemistry
1999

We examined the agonist-dependent sequestration/internalization of dopamine D2 receptor (the long form D2L and short form D2S), which were transiently expressed in COS-7 and HEK 293 cells with or… (More)

Synthesis and release of ( 14 C)acetylcholine in synaptosomes.

Tatsuya Haga
Journal of neurochemistry
1971

klavier (klv), a novel hypernodulation mutant of Lotus japonicus affected in vascular tissue organization and floral induction.

Erika Oka-Kira, Kumiko Tateno, +11 authors Masayoshi Kawaguchi
The Plant journal : for cell and molecular…
2005

A novel hypernodulation mutant line was isolated from Lotus japonicus Miyakojima MG-20 by irradiation with a helium ion beam. This mutant, named klavier (klv), had roots that were densely covered… (More)

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