Tatsushi Fujita

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A simple and quantitative scoring system for evaluating shock was proposed on the analysis of signs, symptoms and laboratory data on 62 patients diagnosed as being in shock. Five clinical features such as systolic blood pressure, pulse rate, hourly urinary output, base excess and mental state, representing functions of vital organs, were graded into 4(More)
The correlation between disseminated intravascular coagulation (DIC) and pulmonary insufficiency following trauma and shock was studied in patients. Serial coagulation tests were performed on nine patients suffering from adult respiratory distress syndrome (ARDS), and six of nine showed the evidence of consumption coagulapathy. Heparin infusion was(More)
Anesthesiologists are frequently involved with the management of patients requiring endotracheal intubation. We have found that serious tracheal lesions such as tracheal ulcerations and tracheoeophageal fistulae are usually preventable with careful management of the upper airways and regulation of endotracheal-tube cuff pressure' ,2. However laryngeal(More)
In this study to investigate whether β-adrenergic receptor systems in the heart are impaired during endotoxemia, we examined two models of septic shock in rats, each of which has a different time course for the shock state. Male Wistar rats were divided into two groups: (1) the LPS (lipopolysaccharide) iv group (Escherichia coli endotoxin 1.0 mg·kg−1 iv(More)
The role of disseminated intravascular coagulation (DIC) in the pathogenesis of adult respiratory distress syndrome (ARDS) was studied in the experimental animals. ARDS was simulated in dogs by the administration of various doses of Escherichia coli endotoxin (Difco). The alveolar surface activity in the group which recived lethal dose of endotoxin (3(More)
Many monitors have been designed for use during carotid endarterectomy (CEA) surgery to detect cerebral ischemia during carotid artery clamping [1]. Electroencephalography (EEG) is one of the monitors often used during CEA surgery. EEG is a useful system for the detection of cerebral ischemia, but it does not detect all cases of cerebral ischemia. We report(More)
The purpose of this study was to determine the efficacy of treatment with anti-tumor necrosis factor (TNF) antibody in preventing the deleterious effects of endotoxin. Polyclonal anti-TNF antibody was produced by immunizing rabbits. Experiments were carried out on 16 rabbits intravenously infused with the lethal dose of lipopolysaccharide (LPS).(More)
Thromboembolism associated with congenital antithrombin III (AT III) deficiency was first reported by Egeberg in 1965 • AT III deficiency leads to a hypercoagulable state' characterized clinically by venous thrombosis of the lower limb and pulmonary embolism. The onset of venous thrombosis is associated with pregnancy or surgery-":". Reports in the(More)
This paper is an introduction of the present status of casualty care in Japan and the role of anesthesiologists. These data were based on our inquiries to the network of casualty critical care "Kyumei-Kyukyu" centers, all over Japan. This network system has been established on financial support by the Ministry of Health to cover regional areas on the(More)
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