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Formatted single-domain antibodies can protect mice against infection with influenza virus (H5N2).
This work continues a series of recently published studies that employ recombinant single-domain antibody (sdAb, or nanobody®) generation technologies to battle viruses by a passive immunization… Expand
Genetic Passive Immunization with Adenoviral Vector Expressing Chimeric Nanobody-Fc Molecules as Therapy for Genital Infection Caused by Mycoplasma hominis
Developing pathogen-specific recombinant antibody fragments (especially nanobodies) is a very promising strategy for the treatment of infectious disease. Nanobodies have great potential for gene… Expand
Passive immunization with a recombinant adenovirus expressing an HA (H5)-specific single-domain antibody protects mice from lethal influenza infection.
One effective method for the prevention and treatment of influenza infection is passive immunization. In our study, we examined the feasibility of creating an antibody-based preparation with a… Expand
A Method for the Parallel and Sequential Generation of Single-Domain Antibodies for the Proteomic Analysis of Human Blood Plasma
- O. S. Goryainova, T. I. Ivanova, M. V. Rutovskaya, S. V. Tillib
- Molecular Biology
- 1 November 2017
A new efficient method for the parallel and sequential stepwise generation of single-domain antibodies to various high-abundance human-plasma proteins has been described. Single-domain antibodies… Expand
Polymorphism of genes for catechol-O-methyltransferase (COMT) and hemochromatosis (HFE) in residents of radiocontaminated regions varying in chromosome aberration frequency
The association between polymorphisms in the COMT and HFE genes, involved in oxidative stress control, on the one hand, and chromosome aberration frequency in lymphocytes, on the other hand, is… Expand
Nanoantibodies for detection and blocking of bioactivity of human vascular endothelial growth factor a165
Nanoantibodies (single-domain antibodies, nanobodies) derived from noncanonical single-chain immunoglobulins provide an attractive tool for in vitro and in vivo diagnostics as well as for development… Expand
A study of chromosome aberrations and markers of oxidative stress (malondialdehyde, plasma total antioxidant activity) among females residing in territories contaminated with radionuclides as a…
COMT val158met Polymorphism and Spinal Analgesia Efficacy of Laparoscopic Surgery for Colorectal Cancer (a Pilot Study)
Цель: оценка влияния SNP val158met гена COMT на эффективность спинальной аналгезии в 1 сутки после лапароскопических операций по поводу колоректального рака. Материал и методы. В пилотном… Expand
Analysis of chromosome lesions in women with gynecological disorders, residing in territories contaminated as a result of the Chernobyl accident
Spontaneous levels of chromosome aberrations in peripheral lymphocytes of 95 women were analyzed in the course of medical examination of residents of Bryansk region territories (Klintsy district, and… Expand