Tatiana G Zybina

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This article deals with the structural and functional organization of polytene chromosomes in mammals. Based on cytophotometric, autoradiographic, and electron microscopic data, the authors put forward a concept of nonclassic polytene chromosomes, with special reference to polytene chromosomes in the mammalian placenta. In cells with nonclassic polytene(More)
An increased activity of membranes of the nuclear envelope (NE) was observed electron microscopically in the trophoblast cells of the rat placenta. The activity of the membranes was manifested as formation of various NE derivatives, such as the annulate lamellae (AL), the intranuclear tubules, and the concentric membranous structures. At the period of(More)
The presence of keratin intermediate filaments is a characteristic of trophoblast differentiation. Meantime, their intracellular localization in the functionally different subtypes of placental trophoblast is poorly investigated in rodent, whereas their placentae are being broadly investigated in recent years as a model of the feto-maternal interaction. The(More)
The supergiant trophoblast cells characteristic of vole placenta prove to be highly invasive being found at the boundary of the decidualized endometrium and myometrium. Their size (100 microm and higher) suggests them to be highly polyploid, though their ploidy was not determined by now. We performed determination of the ploidy level of the supergiant(More)
A cytophotometric study of DNA content has been made for secondary trophoblastic giant cells, which differ morphologically in relation to the stage of the cycle of the polytene nucleus. The ploidy rate varying from 16c to 512c. It is shown that the DNA content of the nuclei with polytene chromosomes in phase G is more stable, corresponding to the 2c(More)
Ultrastructural organization of the rat trophoblast cells in the connective zone of placenta and labyrinth was investigated on the 12-14th days of gestation. A clear distinction was revealed in the cytoplasm ultrastructure of two cell subpopulations within the connective zone of placenta, i.e. glycogen and trophospongium cells. The former display a well(More)
A comparative study was performed of the arrangement of different nucleolar components during differentiation of trophoblast cell populations in the junctional zone of placenta (glycogen cells and trophospongium) and in the secondary giant cells. Each cell type is characterized by specific interrelation of nucleolar components. Some glycogen cells show(More)
Using 3H-thymidine labeling and cytophotometric DNA content measurement in nuclei and mitotic figures, proliferative activity and genome reproduction peculiarities have been studied in highly invasive, primary and secondary giant trophoblast cells (pGTCs and sGTCs, respectively) as well as in the low invasive junctional zone and labyrinth trophoblast cells(More)
Dynamics of genome multiplication during establishment of interrelations between the trophoblast and the glandular epithelium of endometrium was studied in the course of placenta formation in the silver fox. Endometrium response on the embryo implantation exhibits some features of inflammation. In the course of placenta formation the trophoblast gains(More)