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A group of infant onset epilepsies manifest very frequent generalized tonic-clonic seizures (GTC) intractable to medical therapy, which may or may not be accompanied by minor seizures such as myoclonic seizures, absences and partial seizures. They include severe myoclonic epilepsy in infancy (SMEI) and intractable childhood epilepsy with GTC (ICEGTC). They(More)
This study attempted to identify a specific personality disorder (PD) cluster associated with poor outcome after a 4-month course of antidepressant therapy. Subjects were 96 consecutive outpatients with major depression. The Structured Clinical Interview for DSM-III-R (SCID) was used to make Axis I and Axis II diagnoses. To evaluate the net effect of each(More)
Out of the 314 children with partial epilepsies below the age of 15 who had been followed for more than 5 years, 122 children with functional partial epilepsies (FPE) were the subjects of this study. The specific modality of interictal EEG findings reminiscent of that of the Rolandic spikes (Dalla Bernardina, 1982, 1984) was compared between functional and(More)
In 1997 a mental health survey using a 30-item General Health Questionnaire (GHQ-30) and an interview survey of an atomic bombing experience were conducted in survivors of the Nagasaki atomic bombing. Overall psychological distress measured on the basis of the GHQ-30 was greater in the atomic bombing survivors than in the controls. As for the contents of(More)
A retrospective study was carried out on 261 patients with various epilepsies who had undergone convulsive status epilepticus prior to the subsequent onset of epileptic seizures. 1. Convulsive status epilepticus was found more in partial epilepsy and secondary generalized epilepsy at about the same rate, and evidently less in primary generalized epilepsy.(More)
A prospective intraindividual study of WISC-R testing in the 45 children with epilepsy revealed that: 1) antiepileptic drugs, phenobarbital in particular, resulted in a detrimental effect on the WISC-R scores, 2) of the WISC-R subtests, vocabulary tasks of the verbal test were the most susceptible indicators in children whose FSIQ scores either improved or(More)
This study examined the influence of milk casein-derived peptides on cerebral activity after mental stress loading. In a crossover study, 16 male students were given a drink containing peptides (peptide group), or water (control group) before stress loading. The oxyhaemoglobin (HbO(2)) concentration in the prefrontal area of the brain and work efficiency(More)
Of 362 children with therapy-resistant epilepsy, 119 patients had generalized tonic seizures, which were the most common seizure type in patients with generalized epilepsy. The long-term observation of the patients with tonic seizures revealed that their seizures were completely controlled in 27 patients for more than 5 years. The effective antiepileptic(More)
Mollaret's meningitis is a rare disease of unknown etiology, characterized by repeated aseptic meningitis with transient neurological symptoms and quick recovery. The patient, a 16-year-old boy, had episodes of acute encephalitis followed by complete recovery every year from the age of 13 to 16 years. The symptoms at onset were loss of consciousness, a(More)