Our previous results demonstrate the gastroprotective but not ulcerogenic action of glucocorticoids released in response to ulcerogenic stress factors. The present study was undertaken to investigate… (More)
The results overviewed in the present article suggest that glucocorticoids released during acute activation of hypothalamic-pituitary-adrenocortical (HPA) axis are important gastroprotective factors,… (More)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among some of the most commonly used medications. Serious adverse effects induced by NSAIDs may occur not only in the upper gastrointestinal tract,… (More)
The aim of the present work was to study the involvement of glucocorticoid receptors and corticotropinreleasing factor type 2 receptors (CRF-2 receptors) in mediating the analgesic effects of CRF on… (More)
This review provides an analysis of data on the mechanisms of the analgesic action of corticotropin-releasing factor (CRF) on somatic pain sensitivity. Experiments on rats addressed the involvement… (More)
The aim of the study was to verify a dependence of dexamethasone effect on the gastric erosion formation upon duration of the hormonal action. Gastric erosions were induced by indometha cin (35… (More)
We report testing of the suggestion that aggravation of the actions of glucocorticoid treatment on the formation of indomethacin-induced erosions may be mediated by inadequate production of… (More)
We report here our studies of the contribution of the hypothalamo-hypophyseal-adrenocortical system (HHACS) and opioid system to the analgesic effect of corticotropin-releasing factor (CRF) in… (More)
A study was made of the effect of bath-applied hydrocortisone (10(-4) M) on excitatory transmission of the lateral olfactory tract (LOT) - superficial pyramidal cell synapse of the rat olfactory… (More)
Effects of stress during different periods of ontogeny, namely, the prenatal, prepubertal, or their combination (prenatal+prepubertal), on the indices of psychoemotional and tonic pain-related… (More)