Taro Nimura

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OBJECT The "wearing-off" phenomenon often hampers the treatment of Parkinson disease (PD). Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) is known to ameliorate the wearing-off phenomenon, the mechanism by which it does this remains unclear. As part of an inquiry into the mechanism of STN DBS, the authors measured synaptic dopamine(More)
We present a surgical case of a dissecting aneurysm of the right middle cerebral artery associated with subarachnoid hemorrhage and intracranial hemorrhage. A 61-year-old woman with consciousness disturbance and left hemiplegia was referred to our hospital. She had suffered severe headache for a week. CT scan showed a subarachnoid hemorrhage in the right(More)
OBJECT Levodopa-induced dyskinesia (LID) in patients with Parkinson disease (PD) mimics acute dystonic reactions induced by antipsychotic agents, possibly mediated by sigma-receptors; however, there are few reports in which the relationship between sigma-receptors and LID in advanced PD is investigated. The binding potential of cerebellar sigma-receptors(More)
OBJECT The aim of this study was to estimate the impact of stereotactic pallidal surgery on the binding potential of dopamine D2 receptors in patients with advanced Parkinson disease (PD). METHODS Six patients with advanced PD (three men and three women; mean age 56.7 +/- 9.8 years, Hoehn and Yahr stage 3.3 +/- 1.1/3.9 +/- 1.2 [on/off scores], mean +/-(More)
The authors describe a rare case of lumbar discal cyst which produced manifestations similar o lumbar disc herniation. A 33-year-old man, who had had a crick in the back 3 months previously, suffered from severe low back and right lower-extremity pain. The neurological examination showed the L5 radiculopathy through the positive straight leg-raising test,(More)
We report a case of enlargement of a intradiploic epidermoid cyst following head trauma in a 19-year-old man. The patient had a swelling on the right side of his forehead from the time of his birth. He sustained a bruise in this region when he was 15 years old, following which the swelling gradually enlarged. When the diameter of the mass increased to 5 cm,(More)
We retrospectively investigated the effects of subthalamic nucleus stimulation (STN-DBS) on new postoperative onset of cognitive decline and prognostic factors for advanced Parkinson's disease (PD). We studied 39 PD patients who had received bilateral STN-DBS. Clinical symptoms, cognitive function, psychiatric function, and health-related quality of life(More)
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