Tareq Al-maqtari

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Although transplantation of c-kit+ cardiac stem cells (CSCs) has been shown to alleviate left ventricular (LV) dysfunction induced by myocardial infarction (MI), the number of exogenous CSCs remaining in the recipient heart following transplantation and their mechanism of action remain unclear. We have previously developed a highly sensitive and accurate(More)
Although transplantation of c-kit+ cardiac progenitor cells (CPCs) significantly alleviates post-myocardial infarction left ventricular dysfunction, generation of cardiomyocytes by exogenous CPCs in the recipient heart has often been limited. Inducing robust differentiation would be necessary for improving the efficacy of the regenerative cardiac cell(More)
A recent phase I clinical trial (SCIPIO) has shown that autologous c-kit+ cardiac progenitor cells (CPCs) improve cardiac function and quality of life when transplanted into patients with ischemic heart disease. Although c-kit is widely used as a marker of resident CPCs, its role in the regulation of the cellular characteristics of CPCs remains unknown. We(More)
Al-maqtari, Tareq 1979-, "Approaches in the treatment of Parkinson's disease : a focus on stem cell-based therapies." (2012). DEDICATION This Thesis is dedicated to my beloved wife (Hanaan Al-maqtari) and my lovely kids (Bara' ah, Sondos, and Mohammed) for their unlimited love and support. iii ACKNOWLEDGEMENTS It is my pleasure to express my gratitude to my(More)
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