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Oxidant stress-induced loss of IRS-1 and IRS-2 proteins in rat skeletal muscle: role of p38 MAPK.
Oxidative stress is characterized as an imbalance between the cellular production of oxidants and the cellular antioxidant defenses and contributes to the development of numerous cardiovascular andExpand
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Interactions of the advanced glycation end product inhibitor pyridoxamine and the antioxidant alpha-lipoic acid on insulin resistance in the obese Zucker rat.
Oxidative stress and protein glycation can contribute to the development of insulin resistance and complications associated with type 2 diabetes mellitus. The antioxidant alpha-lipoic acid (ALA)Expand
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In vitro oxidant stress causes preferential loss of IRS proteins in rat skeletal muscle
Oxidative stress, the imbalance of oxidant production and the antioxidant defenses in the cell, can impair the functionality of elements of the insulin-signaling pathway that regulates glucoseExpand