Tara E Risling

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Cognitive impairment associated with subtle changes in neuron and neuronal network function rather than widespread neuron death is a feature of the normal aging process in humans and animals. Despite its broad evolutionary conservation, the etiology of this aging process is not well understood. However, recent evidence suggests the existence of a link(More)
Oxidative stress is frequently implicated in diminished electrical excitability of aging neurons yet the foundations of this phenomenon are poorly understood. This study explored links between alterations in cellular thiol-redox state and age-associated decline in electrical excitability in identified neurons (right pedal dorsal 1 [RPeD1]) of the gastropod(More)
This study examined the effect of temperature on volatile concentrations of 2 inhalant anesthetics, isoflurane (ISO) and sevoflurane (SEVO), delivered via open-drop technique, as well as the characteristics of induction and recovery using the open-drop method in mice. Testing revealed that temperature had no effect on the volatile concentration of either(More)
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