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BACKGROUND The role of HBV X protein (HBx) in the development of hepatocellular carcinoma (HCC) has been well studied. However, little is known about the molecular functions of HBV whole-X protein (HBwx), a protein fused with HBx and upstream 56 amino acid, in HCC. In current study, the molecular functions of HBwx in HCC pathogenesis has been investigated,(More)
This paper presents a design and implementation of a low noise phase-locked loop (PLL) based on ring oscillator to provide timing clocks for the analog-to-digital converter (ADC). The ring oscillator consists of four current control delay cells with current-steering amplifier (CSA) circuit. These fully switching differential delay cells are employed to(More)
The effect of hepatitis B immunoglobulin (HBIG) on hepatitis B virus (HBV) DNA load and its protective mechanism are not well understood. Twenty-eight hepatitis B surface antigen (HBsAg)-positive pregnant women and their newborns were assigned to an experimental (n = 12) or control group (n = 16) according to whether they received HBIG during pregnancy. HBV(More)
A single-in-differential-out variable gain wideband LNA without on-chip inductor for CMMB TV tuner is implemented in 0.18 µm CMOS. The LNA provide gain modes ranging from 18 dB to −12 dB with a 6dB step. The LNA exhibits an IIP3 of 7.76 dBm and an NF of less than 2.4 dB at 18 dB gain mode. The output imbalance is only 0.01 dB in amplitude and(More)
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