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OBJECTIVE To evaluate the effect of bone marrow-derived mesenchymal stem cells (BM-MSCs) transplantation on tissue expansion. BACKGROUND Tissue expansion provides a better solution to large defect reconstruction with perfectly matched skin and without deformity at the donor site. How to promote tissue expansion and reduce complications has been a focus in(More)
Flap prefabrication is started with transposition of a vascular pedicle into a donor area that lacks an axial blood supply. Adipose-derived stem cells (ASCs) have been proven beneficial for promoting neovascularization and tissue regeneration in several animal models. Here we investigated the feasibility of applying ASCs as a novel strategy to promote flap(More)
BACKGROUND Resurfacing of facial massive soft tissue defect is a formidable challenge because of the unique character of the region and the limitation of well-matched donor site. In this report, we introduce a technique for using the prefabricated cervicothoracic skin flap for facial resurfacing, in an attempt to meet the principle of flap selection in face(More)
OBJECTIVE To introduce a new prefabricated flap with matched colour, texture, thin enough thickness, large enough dimension and reliability for reconstruction of massive defect of face and neck. METHODS The patients with massive scar of face and neck were selected for treatment with prefabricated flap. Flap prefabrication involved two stages. The(More)
Different XML formats are widely used for data exchange and processing, being often necessary to mutually convert between them. Standard XML transformation languages, like XSLT or XQuery, are unsatisfactory for this purpose since they require writing a separate transformation for each direction. Existing bidirectional transformation languages mean to cover(More)
Model synchronization plays an important role in model- driven software development. Bidirectional model transformation approaches provide techniques for developers to specify the bidirectional relationship between source and target models, while keeping related models synchronized for free. Since models of interest are usually not in a one-to-one(More)
Putback-based bidirectional programming allows the programmer to write only one putback transformation, from which the unique corresponding forward transformation is derived for free. The logic of a putback transformation is more sophisticated than that of a forward transformation and does not always give rise to well-behaved bidirectional programs; this(More)
Endothelial progenitor cells (EPCs) play a significant role in physiological and pathological hypoxia resistance and neovascularization processes. The ability to mobilize EPCs from bone marrow usually indicates a prognostic endpoint of several vascular diseases. Thus, it is of great value to study possible approaches for activating functional EPCs. The(More)
BACKGROUND It is still highly challenging to restore the esthetic neck contour for postburn deformities. In many patients with burns, the back skin remains intact, which is a useful donor site for extensive contracture release. As the main technique, the refinement of the pre-expanded superficial cervical artery (SCA) flaps may improve its application in(More)
BACKGROUND Massive scars of face and neck cause severe esthetic and functional problems in patients. To achieve better outcomes, in this study, we demonstrate the use of the expanded lateral thoracic pedicle flap, which provides a large and thin flap that matches the face and neck area in color and texture with minimal donor site morbidities. METHODS(More)