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The MapReduce model is becoming prominent for the large-scale data analysis in the cloud. In this paper, we present the benchmarking, evaluation and characterization of Hadoop, an open-source implementation of MapReduce. We first introduce HiBench, a new benchmark suite for Hadoop. It consists of a set of Hadoop programs, including both synthetic(More)
The genetics of complex disease produce alterations in the molecular interactions of cellular pathways whose collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer's disease (LOAD), we constructed gene-regulatory networks in 1,647 postmortem brain(More)
To improve software productivity, when constructing new software systems, developers often reuse existing class libraries or frameworks by invoking their APIs. Those APIs, however, are often complex and not well documented, posing barriers for developers to use them in new client code. To get familiar with how those APIs are used, developers may search the(More)
Gastric cancer is a heterogeneous disease with diverse molecular and histological subtypes. We performed whole-genome sequencing in 100 tumor-normal pairs, along with DNA copy number, gene expression and methylation profiling, for integrative genomic analysis. We found subtype-specific genetic and epigenetic perturbations and unique mutational signatures.(More)
Achieving high structural coverage such as branch coverage in object-oriented programs is an important and yet challenging goal due to two main challenges. First, some branches involve complex program logics and generating tests to cover them requires deep knowledge of the program structure and semantics. Second, covering some branches requires special(More)
Object-oriented unit tests consist of sequences of method invocations. Behavior of an invocation depends on the state of the receiver object and method arguments at the beginning of the invocation. Existing tools for automatic generation of object-oriented test suites, such as Jtest and J Crasher for Java, typically ignore this state and thus generate(More)
As the mobile platform continues to pervade all aspects of human activity, and mobile applications, or mobile apps for short, on this platform tend to be faulty just like other types of software, there is a growing need for automated testing techniques for mobile apps. Modelbased testing is a popular and important testing approach that operates on a model(More)
Aspect-oriented software development is gaining popularity with the wider adoption of languages such as AspectJ. To reduce the manual effort of testing aspects in AspectJ programs, we have developed a framework, called Aspectra, that automates generation of test inputs for testing aspectual behavior, i.e., the behavior implemented in pieces of advice or(More)
XACML has become the de facto standard for specifying access control policies for various applications, especially web services. With the explosive growth of web applications deployed on the Internet, XACML policies grow rapidly in size and complexity, which leads to longer request processing time. This paper concerns the performance of request processing,(More)