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- Ulrich Schüller, Vivi M Heine, +12 authors Keith L Ligon
- Cancer cell
- 2008
Whether the brain tumor medulloblastoma originates from stem cells or restricted progenitor cells is unclear. To investigate this, we activated oncogenic Hedgehog (Hh) signaling in multipotent and… (More)
- Vito Turk, Veronika Stoka, +4 authors DÅsan Turk
- Biochimica et biophysica acta
- 2012
It is more than 50 years since the lysosome was discovered. Since then its hydrolytic machinery, including proteases and other hydrolases, has been fairly well identified and characterized. Among… (More)
- Stéphane Bentolila, Wade P. Heller, +4 authors Maureen R Hanson
- Proceedings of the National Academy of Sciences…
- 2012
Transcripts of plant organelle genes are modified by cytidine-to-uridine (C-to-U) RNA editing, often changing the encoded amino acid predicted from the DNA sequence. Members of the PLS subclass of… (More)
- Lizi Wu, Tao Sun, Karla Kobayashi, Ping Gao, James D Griffin
- Molecular and cellular biology
- 2002
The molecular mechanisms by which Notch receptors induce diverse biological responses are not fully understood. We recently cloned a mammalian homologue of the Mastermind gene of Drosophila… (More)
- Yun Zhang, Pengyuan Y. Yang, +12 authors Xiaofan Wang
- Nature Cell Biology
- 2013
The tumour stroma is an active participant during cancer progression. Stromal cells promote tumour progression and metastasis through multiple mechanisms including enhancing tumour invasiveness and… (More)
- Tao Sun, Robert F Hevner
- Nature Reviews Neuroscience
- 2014
The size and extent of folding of the mammalian cerebral cortex are important factors that influence a species' cognitive abilities and sensorimotor skills. Studies in various animal models and in… (More)
- Jinming Huang, Zhihua Ju, +10 authors Jifeng Zhong
- International journal of biological sciences
- 2011
The posttranscriptional gene regulation mediated by microRNA plays an important role in the development and function of male and female reproductive organs and germ cells in mammals, including… (More)
- Jiang Cheng, Zhiwei Zhou, +9 authors Shu-Feng Zhou
- Drug design, development and therapy
- 2015
Lycium barbarum berries, also named wolfberry, Fructus lycii, and Goji berries, have been used in the People's Republic of China and other Asian countries for more than 2,000 years as a traditional… (More)
- Yunzi Chen, Weicheng Liu, +7 authors Yan Li
- Journal of immunology
- 2013
The negative feedback mechanism is essential to maintain effective immunity and tissue homeostasis. 1,25-dihydroxyvitamin D (1,25[OH]2D3) modulates innate immune response, but the mechanism remains… (More)
- Tao Sun, Arnaud Germain, +4 authors Stéphane Bentolila
- Proceedings of the National Academy of Sciences…
- 2013
Plant RNA editing modifies cytidines (C) to uridines (U) at specific sites in the transcripts of both mitochondria and plastids. Specific targeting of particular Cs is achieved by pentatricopeptide… (More)