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Energy consumption is a crucial design concern in wireless ad hoc networks since wireless nodes are typically battery-limited. Multipath routing schemes could exploit multiple disjoint routes between any pair of source and destination node, in order to provide aggregated bandwidth, fault-tolerance and load-balancing properties. A multipath routing protocol(More)
(R)-Roscovitine (CYC202) is often referred to as a "selective inhibitor of cyclin-dependent kinases." Besides its use as a biological tool in cell cycle, neuronal functions, and apoptosis studies, it is currently evaluated as a potential drug to treat cancers, neurodegenerative diseases, viral infections, and glomerulonephritis. We have investigated the(More)
Neurotrophins (NTs) are important regulators for the survival, differentiation and maintenance of different peripheral and central neurons. NTs bind to two distinct classes of glycosylated receptor: the p75 neurotrophin receptor (p75(NTR)) and tyrosine kinase receptors (Trks). Whereas p75(NTR) binds to all NTs, the Trk subtypes are specific for each NT. The(More)
This paper presents a novel approach to characterise applications with respect to their energy consumption by using a set of energy-related metrics, called Green Metrics. These indicators are based on energy consumption measurements, such as indexes of computing resource usage, of environmental impact, and even of development costs required to (re)design an(More)
To estimate the order of importance of factors affecting the stability and maturation of compost, pig feces and corn stalks were co-composted at different aeration rates (AR: 0.24, 0.48, 0.72 L kg(-1)dry matter (DM)min(-1)), C/N ratios (15, 18, 21), and moisture contents (MC: 65%, 70%, 75%). The thermophilic phase with all treatments was long enough to meet(More)
Cellular DNA lesions are efficiently countered by DNA repair in conjunction with delays in cell cycle progression. Previous studies have demonstrated that Rad9, Hus1, and Rad1 can form a heterotrimeric complex (the 9-1-1 complex) that plays dual roles in cell cycle checkpoint activation and DNA repair in eukaryotic cells. Although the 9-1-1 complex has been(More)
Metals and biogenic elements were analyzed from surface sediments collected from Zhelin Bay in the South China Sea in December 2008. The high concentrations of TOC, TN and BSi indicate the high nutrient level and diatom productivity in Zhelin Bay. The concentrations of metals were generally far lower than the effects-range-low (ERL) values that define(More)
The synthesis, preclinical profile, and in vivo efficacy in rat xenograft models of the novel and selective anaplastic lymphoma kinase inhibitor 15b (LDK378) are described. In this initial report, preliminary structure-activity relationships (SARs) are described as well as the rational design strategy employed to overcome the development deficiencies of the(More)
Graphene, the two-dimensional carbon material, has unique electronic, thermal and mechanical properties and holds great promise for a wide range of applications such as nano-electromechanical systems, [ 1–3 ] fl exible/stretchable electronics [ 4,5 ] and nanocomposites. [ 6–8 ] In particular, with its superior electronic transport properties and high fl(More)