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Vascular fibrosis in atherosclerosis.
TLDR
The pathogenesis of vascular fibrosis in atherosclerosis is discussed with focus on the networking among main responsible mediators and the main pathophysiologic factors leading toascular fibrosis will also be discussed. Expand
Effect of Shenzhu Guanxin Recipe (参术冠心方) on patients with angina pectoris after percutaneous coronary intervention: A prospective, randomized controlled trial
TLDR
The combination therapy of SGR and SWMT is effective and safe in patients with angina pectoris after PCI when compared with SWMT alone, and no significant difference in any cardiovascular event was found. Expand
Systems Pharmacology Dissection of Traditional Chinese Medicine Wen-Dan Decoction for Treatment of Cardiovascular Diseases
TLDR
A system pharmacology approach was developed to reveal the underlying molecular mechanisms of a clinically effective herb formula (Wen-Dan Decoction) in treating CVDs, which provides a new way for uncovering the molecular mechanisms and new evidence for clinical application of Wen-DanDecoction in cardiovascular disease. Expand
Ginsenoside Rb1 prevents homocysteine-induced endothelial dysfunction via PI3K/Akt activation and PKC inhibition.
TLDR
It is shown for the first time that Rb1 prevents Hcy-induced endothelial dysfunction via PI3K/Akt activation and PKC inhibition and this findings demonstrate a novel mechanism of the action of R b1 that may have value in prevention of HHcy associated cardiovascular disease. Expand
Ginsenoside Rb1 prevents homocysteine-induced EPC dysfunction via VEGF/p38MAPK and SDF-1/CXCR4 activation
TLDR
This study found that ginsenoside Rb1 reversed the Hcy-induced impairment of adhesive and migratory ability in EPCs which were significantly abolished by CXCR4 antagonist AMD3100 and VEGFR2 inhibitor SU5416 and demonstrated a novel mechanism of the action of R b1 that may have value in prevention of HHcy associated cardiovascular disease. Expand
3,7‐Bis(2‐hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase‐5, prevents monocrotaline‐induced pulmonary arterial hypertension via NO/cGMP activation in rats
TLDR
ICT is more effective in preventing MCT‐induced PAH in rats via NO/cGMP activation compared with ICA and demonstrates a novel mechanism of the action of ICT that may have value in prevention of PAH. Expand
Efficacy and Safety of Huxin Formula in Patients after CABG: A Multicenter, Double-Blind, Randomized Clinical Trial
TLDR
Huxin Formula may improve cardiac function of patients with 3 coronary vessel lesions and relieve symptoms of patientswith cardiac function class II but failed to show superiority in primary outcomes. Expand
Contents Vol. 21, 2014
Regulatory T Cells: A New Target of Chinese Medicine in Treatment of Atherosclerosis
TLDR
Although the underlying mechanisms remain to be elucidated, CM treatment targeting Treg cells might provide a promising and novel future approach for prevention and treatment of AS. Expand
REGULATION OF ONCOGENE C-FOS AND HEAT SHOCK PROTEIN (HSP70) GENE IN BRAIN OF MIDDLE CEREBRAL ARTERY OBSTRUCTIVE RATS
TLDR
The results suggested that the induction of c fos gene correlated with ischemia induced injury, and could be looked as an early reactive marker of brain injury. Expand
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