Tanya Mulcahy

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Bipolar affective disorder (BPAD) is a common psychiatric disorder with complex genetic aetiology. We have undertaken a genome-wide scan in one of the largest samples of bipolar affected sibling pairs (ASPs) using a two-stage approach combining sample splitting and marker grid tightening. In this second stage analysis, we have examined 17 regions that(More)
We have completed the first stage of a two-stage genome wide screen designed to identify chromosomal regions that may harbour susceptibility genes for bipolar affective disorder. The first stage screening sample included 509 subjects from 151 nuclear families recruited within the United Kingdom and Republic of Ireland. This sample contained 154 narrowly(More)
Rapid development in the annotation of human genetic variation has increased the numbers of single nucleotide polymorphisms (SNPs) in candidate genes by several orders of magnitude. The selection of both useful target SNPs for disease-gene association studies and SNPs associated with the treatment response is therefore an increasingly challenging task. We(More)
The absorption of energy from electromagnetic fields always involves the conversion of electromagnetic energy into the heat. Dissipated power density is proportional to dielectric loss. In this work we investigate dielectric loss (complex permittivity) of intrinsic and extrinsic Cz and Fz silicon in the X microwave band. The mechanism of the interaction of(More)
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