Tanya Makarova

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The influence of extremely low frequency magnetic field on rats behavior (working memory, learning, social activity) was examined. Rats were exposed to magnetic fields at three different conditions: exposure 1-50 Hz, 46 mT; DC 65 mTl; exposure II-50 Hz, 46 mTl; DC 14-17 mTl; Exposure III-sham. Field related changes were observed after exposure I: the(More)
Most animal experiments in neurosciences require anesthesia of the experimental animal. For fMRI experiments most neuroscientist would prefer (I) a recoverable anesthesia that would (II) allow strong BOLD responses which are (III) reproducibly obtained for the same animal in repetitive experiments. Strong BOLD responses are particularly needed if weak(More)
It has been found that among white outbred rats with different experience of intraspecies contact four types of reaction to the partner are singled out in the "stranger-resident" test: active, neutral passive, highly-aggressive. Belonging to one or another type is determined by the level and correlation of aggression and intraspecies sociability. Among(More)
Using a method of static simulation, a series of erythromycin A analogs was designed with aldehyde functions introduced instead of one of the methyl substituents in the 3′-N-position of the antibiotic that was potentially capable of forming a covalent bond with an amino group of one of the nucleotide residues of the 23S rRNA in the ribosomal exit tunnel.(More)
We studied the influence of social isolation at the age of 2 months on zoosocial behaviour of mixed-bred male rats with different paw preference. Paw preference was determined in the test of reaching for food in the horizontal tube. The level of aggression but not sociability was found to increase significantly in dextral and ambidextrous late isolants. In(More)
By means of the analysis of probabilistic ethological structures of the intraspecies rats behaviour in the test "stranger-resident" and by the method of isolated destruction of the frontal cortex or the left and right hemispheres,--it is established that the frontal cortex of the left hemisphere regulates the intraspecies sociability and keeps it on a(More)
It was found that intraspecific behaviour of male rats having been transformed in consequence of breeding under the conditions of social isolation could be modified afterwards by an experience of social contacts. Long-term keeping the isolatedly bred rats with their mates in adulthood decreases the level of intraspecific sociability but does not affect the(More)