Tanya Makarova

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Most animal experiments in neurosciences require anesthesia of the experimental animal. For fMRI experiments most neuroscientist would prefer (I) a recoverable anesthesia that would (II) allow strong BOLD responses which are (III) reproducibly obtained for the same animal in repetitive experiments. Strong BOLD responses are particularly needed if weak(More)
Introduction: Animal experimentation in neurosciences requires the use of anesthetics for animal welfare and cooperation. Two of the most widely used anesthetics for functional magnetic resonance imaging (fMRI) of animals are Isofluorane (Iso) and Alpha-Chloralose (AC). Iso is a volatile drug shown to be suitable to obtain fMRI images at low concentrations(More)
Impairment of hemodynamics and metabolism, which is determined by the condition of the hypothalamo--hypophyseal-adrenal system, is very important in the pathogenesis of peritonitis. The cortisol content, the activity of plasma renin, aldosterone, T3 and T4 were studied in 50 patients with diffuse and generalized peritonitis. The regional control group was(More)
Physical agents cause several physical and mental health disorders and reduce human capability for work, in most severe cases they cause disability. Usually the influence of these physical factors takes place in the work environment and depends on the factor's intensity, exposure time, and individual characteristics. Influence is cumulative and may manifest(More)
The thermotropic properties of multilamellar liposomes from egg yolk lecithin, hydrogenized egg yolk lecithin and several mixtures of these two lipids were studied with the application of excimer--forming optical probe pyrene and microcalorimetry. It was discovered that when the proportion of the egg yolk lecithin in the lipid mixture was raised the(More)