Tanya L. Lancaster

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We described an interactive method for correcting spatial distortion in histology samples, applied them to a large set of image data, and quantitatively evaluated the quality of the corrections. We demonstrated registration of histology samples to photographs of macroscopic tissue samples and to MR images. We first described methods for obtaining(More)
We created a method for three-dimensional (3-D) registration of medical images (e.g., magnetic resonance imaging (MRI) or computed tomography) to images of physical tissue sections or to other medical images and evaluated its accuracy. Our method proved valuable for evaluation of animal model experiments on interventional-MRI guided thermal ablation and on(More)
PURPOSE To investigate the ability of magnetic resonance (MR) to monitor radio-frequency (RF) ablation treatments by comparing MR images of thermal lesions to histologically assayed cellular damage. We developed a new methodology using three-dimensional registration for making spatial correlations. MATERIALS AND METHODS A low-field, open MRI system was(More)
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