Tanya Kumar

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Mitochondrial fission mediated by the GTPase dynamin-related protein 1 (Drp1) is an attractive drug target in numerous maladies that range from heart disease to neurodegenerative disorders. The compound mdivi-1 is widely reported to inhibit Drp1-dependent fission, elongate mitochondria, and mitigate brain injury. Here, we show that mdivi-1 reversibly(More)
  • J . Nelson Samuel Jebastin, Tanya Kumar, D . Evangelin
  • 2015
Cancer therapies targeted developing cell cyclebased mechanism that emulates the body’s natural process in order to stop the growth of cancer cells. This approach can limit the damage to normal cells and the accompanying side effects caused by conventional chemotherapeutic agents. Inhibition of histone deacetylase (HDAC) enzymes is emerging as an innovative(More)
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