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OBJECTIVE The clinical significance of the Simpson system for grading the extent of meningioma resection and its role as a predictor of the recurrence of World Health Organization (WHO) Grade I meningiomas have been questioned in the past, echoing changes in meningioma surgery over the years. The authors reviewed their experience in resecting WHO Grade I(More)
BACKGROUND The clinical significance of the Simpson grading system of extent of meningioma resection and its role as a predictor for recurrence of World Health Organization (WHO) grade I meningiomas have been questioned in the past, as microsurgery and knowledge of pathologic details have advanced. METHODS Clinical and radiologic information on 112(More)
INTRODUCTION The present study investigates outcomes in patients undergoing elective primary versus revision fusion surgery for lumbar degenerative pathologies with the use of a large population based database. METHODS A total of 126,044 patients registered in the National Inpatient Sample (NIS) database were identified to have undergone elective fusion(More)
OBJECT The difference in course and outcome of several neurodegenerative conditions and traumatic injuries of the nervous system points toward a possible role of genetic and environmental factors as prognostic markers. Apolipoprotein E (Apo-E), a key player in lipid metabolism, is recognized as one of the most powerful genetic risk factors for dementia and(More)
OBJECTIVE In this study, we validate the utility of navigation in intracranial meningioma excision and evaluate the effectiveness of image guidance surgery based on clinical outcome, extent of resection, and recurrence-free survival (RFS). METHODS Information related to clinical history, use of neuronavigation, neuroimaging, microsurgical dissection, and(More)
Cysts associated with arteriovenous malformations (AVMs) are either secondary to hemorrhage or after radiosurgery. Untreated and unruptured AVMs with large cysts are rare. We here describe a child with medial parietal AVM associated with cyst, without any history of hemorrhage or radiosurgery. Surgical excision led to cure for the patient.
OBJECTIVE Primary glioblastoma multiforme of the spinal cord is a rare entity. The aim of this study was to perform an integrative analysis of patients whose cases were selected from the published studies, and to examine the influence of various factors on overall outcomes. METHODS A PubMed search was performed for literature published from 1938 to 2015(More)
Extraneural metastasis (ENM) in patients with medulloblastoma is a rare but a well-described phenomenon, both in children and adults. Most of the ENM involve bone and bone marrow and rarely involve other solid organs. Subcutaneous and muscular metastasis is an extremely rare event, more so in children, with only two cases documented in the pediatric(More)
Sinus histiocytosis with massive lymphadenopathy or Rosai-Dorfman disease is a rare, but well documented entity. We report a lady who presented with progressive quadriparesis, with cervical extradural lesion on magnetic resonance imaging. She underwent decompression of the lesion and histological diagnosis of the lesion was Rosai-Dorfman disease. On(More)
Split cord malformations (SCM) may be discovered as isolated occult spinal dysraphism or in association with various other overt developmental spinal abnormalities or lesions. However, the occurrence of SCM with intraspinal teratoma is rare. We report 2 cases of teratoma associated with SCM, of which one is intramedullary and the other extradural within(More)